840475P

18:1 (Δ9-Cis) PG

Avanti Research^™ - A Croda Brand

• Synonym(s): 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DOPG; PG(18:1(9Z)/18:1(9Z))
• Empirical Formula (Hill Notation): C₄₂H₇₈O₁₀PNa
• CAS Number: 67254-28-8
• Molecular Weight: 797.03
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• description: 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)
• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 g (840475P-1g); pkg of 2 × 100 mg (840475P-200mg); pkg of 5 × 100 mg (840475P-500mg); pkg of 1 × 25 mg (840475P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

Description

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.

Application

18:1 (Δ9-Cis) PG has been used:

• in the preparation of giant unilamellar vesicle (GUV)
• in the preparation 200 nm large unilamellar vesicles (LUV)
• as a supplement in native macrophage membranes to generate membrane liposomes with an artificially modified electrical charge

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

Packaging

5 mL Clear Glass Sealed Ampule (840475P-200mg)

5 mL Clear Glass Sealed Ampule (840475P-25mg)

5 mL Clear Glass Sealed Ampule (840475P-500mg)

60 mL Amber Wide Mouth Screw Cap Glass Bottle (840475P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3