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17β-Estradiol solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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certified reference material






ampule of 1 mL




1.0 mg/mL in acetonitrile


gas chromatography (GC): suitable
liquid chromatography (LC): suitable


clinical testing
clinical testing


single component solution

storage temp.


SMILES string




InChI key


Gene Information

human ... ESR1(2099)

General description

A Certified Spiking Solution® suitable for use as starting material in calibrators, controls, or linearity standards for a variety of LC/MS or GC/MS applications from endocrinology to clinical and diagnostic testing.

17β-Estradiol belongs to the group of endogenous endocrine disruptors that disturb thyroid activity and function. It is also a sex hormone prescribed under the trade names Vagifem®, Estring®, Evamist, Elestrin®, Estrace®, and Estrogel® as a treatment for hypoestrogenism.


The Certified Reference Material (CRM) in solution can also be used as follows:
  • Electrochemical determination of 17β-Estradiol in river water samples using a reduced graphene oxide and a metal complex porphyrin-based sensor
  • Development of a fluorescence resonance energy transfer (FRET) based aptasensor to determine 17β-Estradiol in environmental water, urine, and milk samples
  • Analysis of milk product samples to estimate 17β-Estradiol by high-performance liquid chromatography (HPLC) coupled with fluorescence detection following its solid phase extraction using graphene/multi-walled carbon nanotubes (MWCNTs)
  • Solid phase extraction of 17β-estradiol and 17α-ethinylestradiol from tap water samples using magnetic graphene oxide (GO)/γ-Fe2O3 nanoparticles for their simultaneous quantification by high-performance liquid chromatography (HPLC) combined with fluorescence detector
  • Multi-residue analysis of 17β-estradiol and 17α-ethinylestradiol in commercial pharmaceutical formulation and urine samples using hanging mercury drop electrode and screen printed carbon electrode

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Elestrin is a registered trademark of Azur Pharma
Estrace is a registered trademark of Warner Chilcott Company, LLC
Estring is a registered trademark of Pfizer Health AB
Estrogel is a registered trademark of Ascend Therapeutics, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Vagifem is a registered trademark of Novo Nordisk A/S Corp.


FlameExclamation mark

Signal Word


Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids



Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

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