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P-069

Supelco

Progesterone solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C21H30O2
CAS Number:
57-83-0
Molecular Weight:
314.46
EC Number:
200-835-2
MDL number:
MFCD00003658
UNSPSC Code:
41116107
PubChem Substance ID:
329820050
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

Gene Information

human ... PGR(5241)

Related Categories

Application


  • Progesterone Residue Analysis in Milk: A study developed a method using a metal-organic framework (UiO-67) to enrich and purify progesterone residues in milk, demonstrating a significant advancement in food safety and hormone residue analysis. This application is crucial for ensuring compliance with safety standards and understanding progesterone′s environmental impact (Shang et al., 2022).

  • Steroid Profiling in Serum: Research on semi-automated serum steroid profiling with tandem mass spectrometry highlights the role of progesterone solutions in developing precise bioanalytical methods. This technique is essential for clinical diagnostics and pharmacokinetic studies, offering detailed insights into hormonal balance and its clinical implications (Rakete et al., 2023).

  • Cancer Research: A cheminformatics analysis incorporated progesterone to assess breast cancer hazards, evaluating how certain chemicals influence estrogen and progesterone synthesis. This research is pivotal for understanding carcinogenic risks associated with hormonal changes, aiding in the development of targeted cancer therapies (Borrel and Rudel, 2022).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K L Bruner-Tran et al.
Minerva ginecologica, 65(2), 199-213 (2013-04-20)
Progesterone action normally mediates the balance between anti-inflammatory and proinflammatory processes throughout the female reproductive tract. However, in women with endometriosis, endometrial progesterone resistance, characterized by alterations in progesterone responsive gene and protein expression, is now considered a central element
J H Check et al.
Clinical and experimental obstetrics & gynecology, 40(1), 37-39 (2013-06-04)
To determine if pregnancy rates following embryo transfer are reduced if the endometrial echo pattern in the late proliferative phase is isoechogenic (IE) vs triple line (TL). Pregnancy and implantation rates were compared according to TL vs IE pattern in
Ratana Sapbamrer et al.
Asia Pacific journal of clinical nutrition, 22(2), 222-228 (2013-05-03)
Isoflavone in soybean and its products have numerous beneficial health effects. A number of clinical studies have demonstrated that dietary soy isoflavone can relieve menopausal symptoms, lower risks of breast cancer, and lower cholesterol and glucose. Among the various effects
Marian Szamatowicz et al.
Ginekologia polska, 84(3), 219-222 (2013-05-25)
Uterine leiomyomata (fibroids) are very common, mostly benign tumors in women of reproductive age. Symptomatic fibroids cause significant morbidity and are characterized by heavy prolonged menstrual bleeding, by pain and pelvic pressure and, in some cases, they may lead to
Guillermo Pablo Vicent et al.
Genes & development, 27(10), 1179-1197 (2013-05-24)
A close chromatin conformation precludes gene expression in eukaryotic cells. Genes activated by external cues have to overcome this repressive state by locally changing chromatin structure to a more open state. Although much is known about hormonal gene activation, how
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