MilliporeSigma

1.00494

SAFC

Parteck® M 100 (Mannitol)

EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, E 421

Sign Into View Organizational & Contract Pricing

Select a Size

Synonym(s):
D-Mannitol
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
MDL number:
E Number:
E421
EC Index Number:
200-711-8

Agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

product line

EMPROVE® ESSENTIAL

form

fine powder

autoignition temp.

410 °C

quality

E 421

particle size

(see specification)

pH

5-7 (20 °C, 100 g/L in H2O)

bp

290-295 °C/4 hPa

mp

164-169 °C

solubility

213 g/L

application(s)

liquid formulation
pharmaceutical
solid formulation

storage temp.

2-25°C

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2

InChI key

FBPFZTCFMRRESA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
1.004191.126351.03668
Parteck® M 100 (Mannitol) EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, E 421

SAFC

1.00494

Parteck® M 100 (Mannitol)

Parteck® M 200 (Mannitol) EMPROVE® ESSENTIAL, Ph. Eur., ChP, JP, USP, E 421

SAFC

1.00419

Parteck® M 200 (Mannitol)

Parteck® Delta M (Mannitol) EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, E 421

SAFC

1.12635

Parteck® Delta M (Mannitol)

Parteck® M DPI EMPROVE® EXPERT, Ph. Eur., BP, JP, USP, E 421

SAFC

1.03668

Parteck® M DPI

form

fine powder

form

fine powder

form

fine powder

form

fine powder

mp

164-169 °C

mp

164-169 °C

mp

164-169 °C

mp

164-169 °C

solubility

213 g/L

solubility

213 g/L

solubility

-

solubility

213 g/L

storage temp.

2-25°C

storage temp.

2-25°C

storage temp.

2-25°C

storage temp.

2-25°C

Quality Level

500

Quality Level

500

Quality Level

500

Quality Level

500

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Parteck® M excipient achieves excellent compressibility while keeping the API stable throughout your manufacturing process and beyond. Based on directly compressible mannitol, it does not require further processing or high compression forces. The unique and large surface area of Parteck® M excipient enables rapid disintegration and quick release regardless of the dosage. It is well suitable for tableting processesusing direct compression or granulation techniques such as wet granulation androller compaction. Parteck® M is available in different particle sizes.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 6

1 of 6

Mannitol Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1007

Mannitol

Mannitol European Pharmacopoeia (EP) Reference Standard

M0200000

Mannitol

D-Mannitol meets EP, FCC, USP testing specifications

Sigma-Aldrich

M8429

D-Mannitol

D-Mannitol BioXtra, ≥98% (HPLC)

Sigma-Aldrich

M9546

D-Mannitol

D-Mannitol ACS reagent

Sigma-Aldrich

M9647

D-Mannitol

D-Mannitol ≥98% (GC)

Sigma-Aldrich

M4125

D-Mannitol

Articles

Use of Mannitol as an Excipient for Solid Drug Formulation

This article describes the advantages of mannitol when used as an excipient in solid drug formulation.

Dry Granulation in Solid Oral Formulation: Advantages of Spray-Dried Mannitol in Roll Compaction

In recent years, mannitol has gained popularity as an excipient in solid dosage formulation due to its beneficial physicochemical properties.

Solid Formulation Development Using Melt-based 3D Printing Technologies

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

Active Pharmaceutical Ingredient (API) Stability in Solid Dose Formulation

This article describes the use of excipients to help address API stability issues.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service