MilliporeSigma

1.02465

SAFC

Calcium chloride dihydrate

EMPROVE® API, Ph. Eur., BP, ChP, JP, USP

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Synonym(s):
Calcium dichloride
Empirical Formula (Hill Notation):
CaCl2 · 2H2O
CAS Number:
Molecular Weight:
147.01
MDL number:
EC Index Number:
600-075-5

agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

product line

EMPROVE® API

form

solid

potency

2630 mg/kg LD50, skin (Rat)

pH

4.5-8.5 (20 °C, 50 g/L in H2O)

mp

176 °C (dec.) (lit.)

solubility

soluble

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-25°C

SMILES string

O.O.Cl[Ca]Cl

InChI

1S/Ca.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2

InChI key

LLSDKQJKOVVTOJ-UHFFFAOYSA-L

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1 of 4

This Item
1.371011.93633208291
vibrant-m

1.02465

Calcium chloride dihydrate

vibrant-m

1.37101

Calcium chloride dihydrate

vibrant-m

1.93633

Calcium chloride dihydrate

vibrant-m

208291

Calcium chloride dihydrate

Quality Level

600

Quality Level

500

Quality Level

-

Quality Level

100

form

solid

form

solid

form

-

form

solid

mp

176 °C (dec.) (lit.)

mp

176 °C (dec.) (lit.)

mp

176 °C (dec.) (lit.)

mp

176 °C (dec.) (lit.)

pH

4.5-8.5 (20 °C, 50 g/L in H2O)

pH

4.5-8.5 (20 °C, 50 g/L in H2O)

pH

-

pH

-

agency

BP

agency

BP, JP, Ph. Eur., USP

agency

-

agency

-

General description

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Calcium chloride dihydrate is typically used in clinical nutrition and in infusion. Calcium Chloride dihydrate cryst. Emprove® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

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Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

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