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1.20078

Millipore

Eshmuno® S

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About This Item

UNSPSC Code:
47101511
Pricing and availability is not currently available.

ligand

(Sulfoisobutyl)

sterility

sterile (Caustic Stable)

product line

Eshmuno®

form

resin

specific analyte(s)

MAbs

parameter

1000 cm/hr flow rate
8 bar max. pressure

matrix active group

polymer, Polyvinyl Ether

mean particle size

85 μm

capacity

165 mg binding capacity (lysozyme/ml of resin)

transition temp

flash point 35 °C (own results)

General description

The first member of the Eshmuno® resin family, designed specifically for highly productive downstream bioprocessing

Features and Benefits

Eshmuno® S chromatography resin enables:

  • Purification of basic and neutral proteins (e.g., antibodies) and peptides specifically designed for highly productive downstream bioprocessing
  • High flow rate applications
  • High separation efficiency over a broad range of flow rates with a rigid matrix and optimized pore structure
  • Tentacle technology which provides high yield, selectivity, and focused elution
  • Multiple CIP and packing cycles with the chemically and physically robust bead, leading to a longer resin lifetime
  • Compatibility with 1 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl and storage solutions 0.1 M NaOH

Packaging

  • 1.20078.0100: Eshmuno® S Resin 100ml
  • 1.20078.0010: Eshmuno® S Resin 10ml
  • 1.20078.0500: Eshmuno® S Resin 500ml
  • 1.20078.5000: Eshmuno® S Resin 5L

Plastic bottle

Analysis Note

Appearance: Milky cream coloured turbid suspension, free from coarse mechanical impurities.
Microscopic evaluation: Spherical particles, no agglomerates, no fines.
Extractable matter (water): ≤ 0.08 %
Ionic capacity: 50 - 100 µeq/ml
Performance test (chymotrypsinogen): 10 - 30 mS/cm
Performance test (lysozyme): 35 - 55 mS/cm
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Protein binding capacity (lysozyme): 120 - 180 mg/ml
Particle size (50-120 µm): ≥ 80 %
Particle size (d50): 75 - 95 µm
Cerium: ≤ 30 µg/g
Endotoxins: ≤ 1.00 EU/ml
TAMC (total aerobic microbial count): ≤ 100 CFU/ml
TYMC (total yeast and mould count): ≤ 100 CFU/ml

Legal Information

Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Flame
GHS02

signalword

Warning

hcodes

H226

Hazard Classifications

Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

95.0 °F

flash_point_c

35 °C

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