1.25252
Chromolith® RP-18 endcapped (monolithic) HPLC Columns
L × I.D. 100 mm x 25 mm Prep Column
Synonym(s):
Chromolith® Prep RP-18 endcapped 100-25 column
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About This Item
UNSPSC Code:
41115709
NACRES:
SB.52
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Product Name
Chromolith® RP-18 endcapped, L × I.D. 100 mm x 25 mm Prep column
material
PEEK column
Quality Level
agency
suitable for USP L1
product line
Chromolith®
feature
endcapped
packaging
1 ea of
extent of labeling
18% Carbon loading
parameter
100 bar pressure
45 °C max. temp.
technique(s)
HPLC: suitable
LC/MS: suitable (Prep LC)
UHPLC-MS: suitable
UHPLC: suitable
Related Categories
General description
Preparative HPLC involves much higher sample loading volumes than analytical chromatography. Consequently, greater sample throughput and separation speed are essential for optimal productivity. These criteria are best fulfilled by Chromolith® Prep RP-18 endcapped columns. The combination of macro and mesopores maximizes separation efficiency and flow rate, while minimizing resistance.
The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost savings due to extended column lifetimes
Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns
The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost savings due to extended column lifetimes
Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns
Application
- Simultaneous determination of eight arginine-related metabolites in cellular extracts using liquid chromatography-tandem mass spectrometry.: This study explores the usage of the Chromolith® RP-18 endcapped column for precise metabolic profiling, showcasing its effectiveness in analyzing arginine-related metabolites with high resolution and throughput (Amatya et al., 2020).
- Rapid Determination of 30 Polyphenols in Tongmai Formula, a Combination of Puerariae Lobatae Radix, Salviae Miltiorrhizae Radix et Rhizoma, and Chuanxiong Rhizoma, via Liquid Chromatography-Tandem Mass Spectrometry.: The use of Chromolith® RP-18 endcapped allowed for the fast and efficient separation of polyphenols in complex herbal formulations, illustrating its capabilities in herbal chemistry applications (Wang et al., 2017).
- Simultaneous Liquid Chromatographic Determination of Ebastine with Two Sympathomimetic Drugs Using a Monolithic Column.: This research highlights the Chromolith® RP-18 endcapped column′s ability to simultaneously analyze multiple compounds, thereby providing a method that improves the efficiency of pharmaceutical analyses (Ibrahim and Wahba, 2017).
Analysis Note
Pressure: ≤ 20 bar
Theoretical Plates (N/m) (Anthracene): ≥ 40000
Capacity factor (Anthracene): 3.0 - 4.5
Tailing (USP): 0.8 - 1.4 %
separation factor (anthracene/progesterone): 1.9 - 2.5
Theoretical Plates (N/m) (Anthracene): ≥ 40000
Capacity factor (Anthracene): 3.0 - 4.5
Tailing (USP): 0.8 - 1.4 %
separation factor (anthracene/progesterone): 1.9 - 2.5
Legal Information
Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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