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Chromolith® RP-18 endcapped

L × I.D. 10 mm x 4.6 mm guard cartridges (3 pieces)

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Chromolith® RP-18 endcapped 10-4.6 guard cartridges (3 pieces)


PEEK column

Quality Level


suitable for USP L1

product line





pkg of 3 ea

extent of labeling

18% Carbon loading


400 bar pressure
45 °C max. temp.


HPLC: suitable
LC/MS: suitable
mass spectrometry (MS): suitable (High)

column L × I.D.

1 cm × 4.6 mm


monolithic silica

matrix active group

C18 bonding phase

pore size

13 nm mesoporosity
2 μm macroporosity

operating pH range


separation technique

reversed phase

storage temp.

no temp limit

Related Categories

General description

Although the Chromolith® columns are well known for their robustness and longevity, guard columns are available to prolong the lifespan of Chromolith® analytical columns even further. These guard cartridges require a special holder.
Chromolith® RP-18 endcapped, 10-4.6 guard cartridges are extremely easy to use. The guard cartridges are simply added directly in front of the main column to protect it from chemical or mechanical contamination. Due to the benefits of monolithic technology, and the convenience of Chromolith® guard columns, they are also popular for use with classical particulate columns. Moreover, guard columns can be used as trap columns when large sample volumes are to be injected. Guard columns should be changed frequently in order to avoid excessive accumulation of impurities.

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith® RP-18 endcapped, 10-4.6 guard cartridges are used with the Chromolith® Guard Cartridge Holder 10 mm x 4.6 mm [1.52033]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Analysis Note

visual control (for delivery): passes test

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

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Monolithic silica HPLC columns enable high-throughput analysis at low back pressure without loss of separation efficiency or peak capacity.

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