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Sigma-Aldrich

Cathepsin B Substrate III, Fluorogenic

Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.

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Synonym(s):
Cathepsin B Substrate III, Fluorogenic, Z-RR-AMC, 2HCl
Empirical Formula (Hill Notation):
C30H39N9O6 · 2HCl
Molecular Weight:
694.61

Quality Level

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

color

white

solubility

DMSO: 5 mg/mL
water: soluble

fluorescence

λex 360-380 nm
λem 430-460 nm

shipped in

ambient

storage temp.

−20°C

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218739

Caspase-1 Substrate X, Fluorogenic

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

form

lyophilized solid

form

solid

form

lyophilized solid

form

lyophilized

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

color

white

color

bright yellow

color

white

color

-

shipped in

ambient

shipped in

wet ice

shipped in

ambient

shipped in

ambient

General description

Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity (excitation maximum: 380 nm; emission maximum: 460 nm).
Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.

Biochem/physiol Actions

Cell permeable: no
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Arg-Arg-AMC, 2HCl

Other Notes

Hiwasa, T., et al. 1987. FEBS Lett.211, 23.
Manson, R.W., et al. 1985. Biochem. J.226, 233.
Tanaka, M., et al. 1985. Life Sci. 36, 1217.
Docherty, K., et al. 1984. J. Biol. Chem.259, 6041.
Barrett, A.J., and Kirschke, H. 1981. Methods Enzymol.80, 535.
Barrett, A.J. 1980. Biochem. J.187, 909.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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