220202
CHAPSO
Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.
Synonym(s):
CHAPSO, 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
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About This Item
Empirical Formula (Hill Notation):
C32H58N2O8S
CAS Number:
Molecular Weight:
630.88
MDL number:
UNSPSC Code:
12161902
NACRES:
NA.25
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Quality Level
assay
>98% (TLC)
form
solid
mol wt
micellar wt 9960
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
aggregation number
11
color
white
CMC
8 mM
solubility
water: soluble
General description
Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state (aggregation number: 11; CMC: 8 mM; micellar weight: 9960). Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Has a higher solubility than CHAPS because of its more polar head group.
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 3 days at 4°C.
Other Notes
Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA77, 4623.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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