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P5884

Sigma-Aldrich

Brij® 58

average Mn ~1124

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Synonym(s):
Polyethylene glycol hexadecyl ether, Polyoxyethylene (20) cetyl ether
Linear Formula:
HO(CH2CH2O)20C16H33
CAS Number:
Beilstein:
1899885
MDL number:
PubChem Substance ID:
NACRES:
NA.25

description

non-ionic

Quality Level

form

solid

mol wt

micellar avg mol wt 79,000
average Mn ~1124

aggregation number

70

technique(s)

protein quantification: suitable

CMC

0.08 mM (20-25°C)

mp

~38 °C

transition temp

cloud point >100 °C

HLB

16

SMILES string

CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C56H114O21/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-58-19-21-60-23-25-62-27-29-64-31-33-66-35-37-68-39-41-70-43-45-72-47-49-74-51-53-76-55-56-77-54-52-75-50-48-73-46-44-71-42-40-69-38-36-67-34-32-65-30-28-63-26-24-61-22-20-59-18-16-57/h57H,2-56H2,1H3

InChI key

NLMKTBGFQGKQEV-UHFFFAOYSA-N

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1 of 4

This Item
3888314362408.14727
Brij® 58 average Mn ~1124

Sigma-Aldrich

P5884

Brij® 58

BRIJ® O20 average Mn ~1,150

Sigma-Aldrich

436240

BRIJ® O20

Brij® 58 for synthesis

Sigma-Aldrich

8.14727

Brij® 58

form

solid

form

solid

form

-

form

solid

mol wt

micellar avg mol wt 79,000, average Mn ~1124

mol wt

average Mn ~330

mol wt

average Mn ~1,150

mol wt

-

aggregation number

70

aggregation number

-

aggregation number

-

aggregation number

-

technique(s)

protein quantification: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable, protein quantification: suitable

technique(s)

-

CMC

0.08 mM (20-25°C)

CMC

-

CMC

-

CMC

-

General description

Brij 58 is a nonionic surfactant or detergent for protein extraction and permeabilization of cells. It may be used in the preparation of yeast spheroplasts.

Application

Polyethylene glycol hexadecyl ether, or Brij 58, has been used in a study to assess properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons. It has also been used in a study to investigate RNase-sensitive constraint of bacterial nucleoid structure.

Legal Information

Brij is a registered trademark of Croda International PLC

Pictograms

Environment

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

302.0 °F - closed cup

Flash Point(C)

150 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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MMYOMAG-74K-13

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Brij® 35 solution

Photodestruction of BDE-99 in micellar solutions of nonionic surfactants of Brij 35 and Brij 58
Li, X., et al.
Chemosphere, 78, 8-8 (2010)
Study of surface and solution properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons
Panda
Journal of Molecular Liquids, 163, 6-6 (2011)
M Kellermayer et al.
Journal of cellular physiology, 159(2), 197-204 (1994-05-01)
The plasma membrane of erythrocytes, as of other cells, is thought to act as the barrier responsible for maintaining intracellular gradients of most ions and small molecular species between the cell and its environment. Controlled application of the nonionic detergent
Macromolecular crowding can account for RNase-sensitive constraint of bacterial nucleoid structure
Foley, P., et al
Biochemical and Biophysical Research Communications, 395, 6-6 (2010)
Preparation of extracts from prokaryotes.
M Cull et al.
Methods in enzymology, 182, 147-153 (1990-01-01)

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