233480

Coagulation Factor XI, Human Plasma

Coagulation Factor XI, Human Plasma, CAS 9013-55-2, is a native coagulation factor XI with two identical polypeptide chains linked by disulfide bond. It is activated to Factor XIa by Factor XIIa.

• Synonym(s): Coagulation Factor XI, Human Plasma
• CAS Number: 9013-55-2
• UNSPSC Code: 12352202
• NACRES: NA.77

Properties

• Quality Level: 100
• form: liquid
• specific activity: ≥170 units/mg protein (clotting assay)
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Description

General description

Coagulation Factor XI, Human Plasma, CAS 9013-55-2, is a native coagulation factor XI with two identical polypeptide chains linked by disulfide bond. It is activated to Factor XIa by Factor XIIa.

Native coagulation factor XI from human plasma. Consists of two identical polypeptide chains linked by disulfide bonds, that yield a single band at 80 kDa upon reduction with β-mercaptoethanol. In vivo, Factor XI is activated to Factor XIa by Factor XIIa.

Native coagulation factor XI from human plasma. Consists of two identical polypeptide chains linked by disulfide bonds, that yield a single band at 80,000 on reduction with β-mercaptoethanol. In vivo, Factor XI is activated to Factor XIa by Factor XIIa.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Analysis Note

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

single band by SDS-PAGE

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg