Skip to Content
MilliporeSigma
All Photos(1)

Documents

264101

Millipore

Deoxycholic Acid sodium

An ionic detergent for the solubilization of membrane-bound proteins.

Sign Into View Organizational & Contract Pricing

Synonym(s):
Sodium deoxycholate, 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
Empirical Formula (Hill Notation):
C24H39NaO4
CAS Number:
Molecular Weight:
414.55
Beilstein/REAXYS Number:
3581950
MDL number:
UNSPSC Code:
12161902
NACRES:
NA.21

Quality Level

assay

≥96% (TLC)

form

powder

mol wt

micellar avg mol wt 1200-5000
micellar wt 1700-4200

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

aggregation number

3-12
4 - 10

color

white to off-white

pKa 

6.2

CMC

2-6 mM (20-25°C)
4 - 8 mM

solubility

H2O: 2%, clear, colorless

cation traces

heavy metals: ≤20.0 ppm

HLB

16

shipped in

ambient

storage temp.

15-25°C

SMILES string

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

InChI key

FHHPUSMSKHSNKW-SMOYURAASA-M

Looking for similar products? Visit Product Comparison Guide

General description

An ionic detergent for the solubilization of membrane-bound proteins (aggregation number: 4-10; CMC: 4-8 mM; micellar weight: 1700-4200; pKa 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).
An ionic detergent for the solubilization of membrane-bound proteins. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 4-10.

Warning

Toxicity: Harmful (C)

Other Notes

Pai, R., et al. 2004. Mol. Biol. Cell15 2156.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service