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C6445

Sigma-Aldrich

Sodium cholate hydrate

BioXtra, ≥99%

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Synonym(s):
3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt
Empirical Formula (Hill Notation):
C24H39NaO5 · xH2O
CAS Number:
Molecular Weight:
430.55 (anhydrous basis)
Beilstein/REAXYS Number:
3582354
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

description

anionic

Quality Level

product line

BioXtra

assay

≥99%

form

powder

mol wt

micellar avg mol wt 900-1300

aggregation number

2-3

impurities

≤0.05% Phosphorus (P)
≤0.1% Insoluble matter

CMC

9-15 mM (20-25°C)

solubility

H2O: 1 M, clear, faintly yellow to yellow

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

HLB

18

SMILES string

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI

1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1

InChI key

MUVVIYFKOVLQHL-RCVKHMDESA-M

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1 of 4

This Item
27029C9282S1702
vibrant-m

C6445

Sodium cholate hydrate

Premium Grade
vibrant-m

27029

Sodium cholate hydrate

-
vibrant-m

C9282

Sodium cholate hydrate

-
vibrant-m

S1702

Sodium cholate hydrate

-
assay

≥99%

assay

≥97.0% (dried material, NT)

assay

≥99.0% (HPLC)

assay

-

aggregation number

2-3

aggregation number

2-3

aggregation number

2-3

aggregation number

2-3

cation traces

Al: ≤0.005%, Cu: ≤0.0005%, K: ≤0.005%, NH4+: ≤0.05%, Zn: ≤0.0005%, Ca: ≤0.005%, Mg: ≤0.0005%, Fe: ≤0.0005%, Pb: ≤0.001%

cation traces

-

cation traces

-

cation traces

-

HLB

18

HLB

18

HLB

18

HLB

18

description

anionic

description

anionic

description

anionic

description

-

General description

Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins.

Application

Sodium cholate hydrate has been used in a study to assess infiltration of pressurized promoter solutions in a mesoporous silica.
Sodium cholate hydrate has been used:
  • as a component of biofilm growth media along with tryptic soy broth (TSB) to test the effects of each bile salt on biofilm formation
  • as a detergent to study its effect on cannabinoid receptor 1 (CB1) detection by western blot
  • as a promoter to prepare solution B for the synthesis of tungsten disulfide (WS2) on a SiO2/Si wafer

Features and Benefits

  • pH range 5-8
  • Suitable for membrane technology and culture media

hcodes

Hazard Classifications

Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Current protocols in protein science, 98(1), e100-e100 (2019-11-21)
Lipid nanodiscs provide a native-like lipid environment for membrane proteins, and they have become a valuable platform for the study of membrane biophysics. A range of biophysical and biochemical analyses are enabled when membrane proteins are captured in lipid nanodiscs.
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Protocols

In a typical dispersion procedure, a surfactant is adsorbed on the single-walled carbon nanotubes (SWCNTs) surface and the solution is sonicated, resulting in the debundling or exfoliation of the carbon nanotubes.

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