ABN44
Anti-FGF10 Antibody
from rabbit, purified by affinity chromatography
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All Photos(5)
Synonym(s):
Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse, human
species reactivity (predicted by homology)
rhesus macaque (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... FGF10(2255)
General description
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor family and plays an essential role in the regulation of cell differentiation, tissue repair, tumor growth, embryonic development, and cell proliferation. Mutations in FGF10 have been associated lacrimo-auriculo-dento-digital syndrome (LADDS) which is a form of ectodermal dysplasia.
Immunogen
KLH-conjugated linear peptide corresponding to human FGF10.
Application
Detect FGF10 using this Anti-FGF10 Antibody validated for use in WB, IH(P).
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Western Blot Analysis: 0.5 µg/mL from a representative lot detected FGF10 on 10 µg of mouse embryo tissue lysate.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected FGF10 in mouse epithelial cells, mouse liver, human brain, and human cerebellum tissues.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected FGF10 in mouse epithelial cells, mouse liver, human brain, and human cerebellum tissues.
Quality
Evaluated by Western Blot in A549 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected FGF10 on 10 µg of A549 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected FGF10 on 10 µg of A549 cell lysate.
Target description
~23 kDa observed
Physical form
Affinity purified
Purified Rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4) and 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
A549 cell lysate
A549 cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Nan Wang et al.
Cell proliferation, 55(11), e13315-e13315 (2022-07-20)
Ultraviolet light B (UVB) irradiation can induce skin injury and result in keratinocytes proliferation inhibition. However, the molecular understanding of the repair during UVB-induced cell proliferation inhibition remains poorly understood. The purpose of this study was to explore the role
Shawn Liang et al.
Development (Cambridge, England), 145(2) (2018-01-24)
The developmental program that regulates thyroid progenitor cell proliferation is largely unknown. Here, we show that branching-like morphogenesis is a driving force to attain final size of the embryonic thyroid gland in mice. Sox9, a key factor in branching organ
Handeng Lyu et al.
Cell reports, 41(12), 111863-111863 (2022-12-22)
In injured airways of the adult lung, epithelial progenitors are called upon to repair by nearby mesenchymal cells via signals transmitted through the niche. Currently, it is unclear whether repair is coordinated by the mesenchymal cells that maintain the niche
Albina F Ramalho et al.
Journal of neuroinflammation, 15(1), 10-10 (2018-01-11)
The consumption of large amounts of dietary fats activates an inflammatory response in the hypothalamus, damaging key neurons involved in the regulation of caloric intake and energy expenditure. It is currently unknown why the mediobasal hypothalamus is the main target
Lemonia Chatzeli et al.
Journal of anatomy, 238(6), 1371-1385 (2021-01-18)
A common question in organ regeneration is the extent to which regeneration recapitulates embryonic development. To investigate this concept, we compared the expression of two highly interlinked and essential genes for salivary gland development, Sox9 and Fgf10, during submandibular gland
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