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MAB2154

Sigma-Aldrich

Anti-P-Selectin Antibody, clone P8G6

clone P8G6, Chemicon®, from mouse

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Synonym(s):
CD62P, Granule Membrane Protein-140, GMP-140, Platelet Activation Dependent Granule-external Membrane Protein, PADGEM
eCl@ss:
32160702

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

P8G6, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SELP(6403)

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This Item
SAB4701010SAB1406424SAB4700941
antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

-

clone

P8G6, monoclonal

clone

HI62P, monoclonal

clone

polyclonal

clone

AK4, monoclonal

species reactivity

human

species reactivity

-

species reactivity

human

species reactivity

nonhuman primates, human

manufacturer/tradename

Chemicon®

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

-

technique(s)

ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable

technique(s)

flow cytometry: 2 μg/mL

technique(s)

western blot: 1 μg/mL

technique(s)

flow cytometry: 4 μg/mL

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Specificity

Human P Selectin

Immunogen

IL-1beta activated HUVEC (human)

Application

Detect P-Selectin using this Anti-P-Selectin Antibody, clone P8G6 validated for use in ELISA, IP, IC, IH.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue

Immunocytochemistry

Immunoprecipitation

ELISA

Inhibits P Selectin dependent interactions

Inhibits platelet binding to monocytes

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)

Physical form

Format: Purified
Purified in 0.02M PBS, 0.25M NaCl, pH 7.6 with 0.1% NaN3. Liquid

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Tarek Khreiss et al.
Circulation, 110(17), 2713-2720 (2004-10-20)
Plasma C-reactive protein (CRP) level is a powerful predictor of cardiovascular events. However, it is not known whether CRP could affect neutrophil-platelet adhesion and neutrophil aggregation, key events in acute coronary syndromes. Emerging in vitro evidence suggests that some bioactivities
Michael G Sugiyama et al.
Journal of virology, 90(4), 1812-1823 (2015-12-08)
Lung injury after influenza infection is characterized by increased permeability of the lung microvasculature, culminating in acute respiratory failure. Platelets interact with activated endothelial cells and have been implicated in the pathogenesis of some forms of acute lung injury. Autopsy

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