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Anti-Mucin 5B Antibody, clone MDA-3E1

clone MDA-3E1, from mouse

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Mucin 5 subunit B

biological source


Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies


MDA-3E1, monoclonal

species reactivity

human, mouse


antibody small pack of 25 μL


immunohistochemistry: suitable (paraffin)
western blot: suitable



NCBI accession no.

UniProt accession no.

shipped in


target post-translational modification


Gene Information

mouse ... Muc5B(74180)

Related Categories

General description

Mucin 5, subtype B, tracheobronchial (UniProt: E9Q5I3; also known as MUC5B ) is encoded by the Muc5b gene (Gene ID: 74180) in murine species. Mucins are high molecular weight glycoproteins that consist of a mucin core protein and O-linked carbohydrates. Mucins are present on the surface of, and are secreted by, many glandular epithelial cells. They provide a barrier between the luminal membranes of cells in the epithelium and their environment. Mucins consist of a nonglobular protein backbone (apomucin) and many O-linked glycans. The two principal polymeric mucins are reported in the airways. They are Mucin 5ac that is produced at low levels under healthy conditions, but increases during allergic inflammation or parasitic infection, and Mucin 5B that is produced at substantial levels under healthy conditions and modestly increases under conditions of allergic inflammation Mucin 5B is shown to be abnormally expressed in gastric carcinoma. (Ref.: Ren, B et al. (2015). (Biosci Rep. 35(3): e00220).


Clone MDA-3E1 detects Mucin 5b in human and murine species, it targets an epitope within 20 amino acids from the N-terminal half.


A linear peptide corresponding to 20 amino acids from the N-terminal half of murine Mucin 5 subunit B.


Anti-Mucin 5B, clone MDA-3E1 , Cat. No. MABT899, is a mouse monoclonal antibdoy that detects Mucin 5b and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting.
Immunohistochemistry Analysis: A representative lot detected Muc5b in Immunohistochemistry applications (Ren, B., et. al. (2015). Biosci Rep. 35(3), e00220).

Western Blotting Analysis: A representative lot detected Muc5b in Western Blotting applications (Ren, B., et. al. (2015). Biosci Rep. 35(3); e00220).
Research Category
Inflammation & Immunology


Evaluated by Immunohistochemistry in human nasal mucosal tissue.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Muc5b in human nasal mucosal tissue.

Target description

515.44 kDa calculated. The actual molecular weight of the glycosylated protein may be up to 10-fold higher.

Physical form

Format: Purified
Protein G purified
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to lot specific datasheet.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

12 - Non Combustible Liquids




Not applicable


Not applicable

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David L Goldblatt et al.
British journal of pharmacology, 177(10), 2256-2273 (2020-01-23)
Respiratory viral infections play central roles in the initiation, exacerbation and progression of asthma in humans. An acute paramyxoviral infection in mice can cause a chronic lung disease that resembles human asthma. We sought to determine whether reduction of Sendai

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