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03117057001

Roche

Bovine Serum Albumin Fraction V, heat shock, fatty acid free

from bovine serum

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About This Item

UNSPSC Code:
12352106
NACRES:
NA.21

biological source

bovine

Quality Level

assay

≥98%

form

lyophilized

packaging

pkg of 100 g

manufacturer/tradename

Roche

pH

~7.0

shipped in

wet ice

storage temp.

2-8°C

General description

BSA is a single polypeptide chain consisting of about 583 amino acid residues and no carbohydrates. At pH 5-7, it contains 17 intra-chain disulfide bridges and one sulfhydryl group.

Application

  • Pharmacological assays; ion-binding, transport, or immunological studies
  • Fatty acid and lipid research
  • Stabilization of proteins and enzymes against proteolysis and denaturation

Biochem/physiol Actions

The fatty acids that are insoluble in circulating plasma are transported primarily by serum. The human serum albumin and bovine serum albumin share 76% sequence homology. Being the most abundant protein in the circulatory system, it participates in the maintenance of blood pH and carries several endogenous and exogenous compounds, including fatty acids, metal, amino acids, steroids and drugs.

Quality

Purity: ≥98% albumin (electrophoresis), ≥98% protein
Contaminants: ≤1.2mg total fatty acids/g dry powder, ≤30ppm heavy metals, immunoglobulins are not detectable (by Ouchterlony)

Specifications

Moisture: ≤5%

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Prakrith Vijey et al.
Platelets, 29(6), 583-588 (2018-07-27)
Megakaryocytes (MKs) are specialized precursor cells committed to producing and proliferating platelets. In a cytoskeletal-driven process, mature MKs generate platelets by releasing thin cytoplasmic extensions, named proplatelets, into the sinusoids. Due to knowledge gaps in this process and mounting clinical
Putnam F, et al.
The Plasma Proteins: Structure, Function, and Genetic Control, 5 (2012)
Using BODIPY FL-Sphingolipid Analogs to Study Sphingolipid Metabolism in Mouse Embryonic Stem Cells.
Fan, et al.
Bio-protocol, 12 (2022)
Emilio P Mottillo et al.
Methods in enzymology, 538, 263-278 (2014-02-18)
Intracellular lipolysis is an important cellular process in key metabolic tissues, and while much is known about the enzymatic basis of lipolysis, our understanding of how these processes are organized and regulated within cells is incomplete. Lipolysis takes place on
Chuanyan Wu et al.
Nature communications, 12(1), 6486-6486 (2021-11-12)
The hepatokine follistatin is elevated in patients with type 2 diabetes (T2D) and promotes hyperglycemia in mice. Here we explore the relationship of plasma follistatin levels with incident T2D and mechanisms involved. Adjusted hazard ratio (HR) per standard deviation (SD)

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