ATPDS-RO

Adenosine 5′-triphosphate disodium salt trihydrate

=99%, pkg of 1 g (10519979001), pkg of 5 g (10519987001)

• Synonym(s): ATP
• Empirical Formula (Hill Notation): C₁₀H₂₀N₅Na₂O₁₆P₃
• CAS Number: 51963-61-2
• Molecular Weight: 605.19
• MDL number: MFCD00150754
• UNSPSC Code: 41106305
• PubChem Substance ID: 329773088

Properties

• Quality Level: 100
• description: Disodium salt
• assay: 99%
• form: crystals
• mol wt: 507.2 (ATP); M_r 551.14 (ATP-Na2)
• packaging: pkg of 1 g (10519979001); pkg of 5 g (10519987001)
• manufacturer/tradename: Roche
• Storage temp.: 2-8°C
• SMILES string: O.O.O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.3H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;3*1H2/q;2*+1;;;/p-2/t4-,6-,7-,10-;;;;;/m1...../s1
• Inchi Key: MWEQTWJABOLLOS-AZGWGOJFSA-L

Description

General description

The special quality of ATP contains highly purified Adenosine-5′-triphosphate in crystal form.

Application

Adenosine 5′-triphosphate disodium salt trihydrate has been used:

• in analyzing the ATP turnover cycle of microtubule motors
• for activating the NLR family pyrin domain containing 3 (NLRP3) inflammasome to perform in vitro stimulation of bone marrow-derived dendritic cells (BMDCs)
• for in vitro ubiquitination

It is also suitable for the luminometric determination of luciferase (Luc) activity in cell extracts.

Biochem/physiol Actions

Adenosine 5′-triphosphate (ATP) is a key energy currency, with high phosphate transfer potential, in all living organisms. ATP participates in several biological processes such as membrane transport, muscle contraction and synthesis, and degradation of biological molecules. It serves as an intracellular and extracellular signaling molecule in certain cellular processes such as cell motility, organ development, neurotransmission, and insulin secretion. Adenosine 5′-triphosphate (ATP) acts as a substrate for proteins of the kinesin superfamily.

Preparation Note

Storage conditions (working solution): The reconstituted aqueous solution is stable at 2 to 8 °C for one week.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable