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00840595

Vitexin

primary reference standard

Synonym(s):

4′,5,7-Trihydroxyflavone 8-C-glucoside, 8-C-Glucosylapigenin, Apigenin 8-C-glucoside, Orientoside

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About This Item

Empirical Formula (Hill Notation):
C21H20O10
CAS Number:
3681-93-4
Molecular Weight:
432.38
Beilstein/REAXYS Number:
67796
EC Number:
222-963-8
MDL number:
MFCD00017456
UNSPSC Code:
85151701
PubChem Substance ID:
329747149
NACRES:
NA.24

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccc(O)cc4

InChI

1S/C21H20O10/c22-7-14-17(27)18(28)19(29)21(31-14)16-11(25)5-10(24)15-12(26)6-13(30-20(15)16)8-1-3-9(23)4-2-8/h1-6,14,17-19,21-25,27-29H,7H2/t14-,17-,18+,19-,21+/m1/s1

InChI key

SGEWCQFRYRRZDC-VPRICQMDSA-N

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General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Standard in the analysis of herbal medicinal products

Other Notes

This compound is commonly found in plants of the genus: cannabis crataegus glycyrrhiza humulus

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
HWI01043-2
HWI01043-1
HWI01043
HWI00344

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Tae-Gyu Nam et al.
Food chemistry, 170, 97-101 (2014-10-13)
It is known that common buckwheat sprouts contain several flavonoids, including orientin, isoorientin, vitexin, isovitexin, rutin, and quercetrin, whereas tartary buckwheat sprouts contain only rutin. In this study, we evaluated flavonoids present in buckwheat sprouts and identified a previously unreported
Hayoung Yoo et al.
Inflammation, 37(5), 1705-1717 (2014-04-29)
High mobility group box-1 (HMGB1) protein acts as a late mediator of severe vascular inflammatory conditions. Orientin has been known to have anxiolytic and antioxidative activities. However, the effect of orientin on HMGB1-induced inflammatory response has not been studied. We
Maryam Hamzeh-Mivehroud et al.
Archiv der Pharmazie, 347(10), 738-747 (2014-06-24)
Aldehyde oxidase (AO), an important enzyme in the biotransformation of drugs and xenobiotics, is inhibited by flavonoids. This enzyme can metabolize both aldehydes and N-heterocycles. In this work, a set of 15 flavonoids was assessed for inhibitory activity on the
Xin-shuai Wang et al.
Phytotherapy research : PTR, 29(3), 366-372 (2014-12-03)
In traditional therapy with Chinese medicine, vitexin has several pharmacological properties, including antinociceptive, antispasmodic, antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. Recently, vitexin was shown to protect the heart against ischemia/reperfusion injury in an in vitro model by inhibiting apoptosis. The
N Singh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 968, 105-111 (2014-04-08)
SIRT6 is a histone deacetylase that has been proposed as a potential therapeutic target for metabolic disorders and the prevention of age-associated diseases. Thus the identification of compounds that modulate SIRT6 activity could be of great therapeutic importance. We have
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