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L-Lysine hydrochloride solution

100 mM amino acid in 0.1 M HCl, analytical standard

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Empirical Formula (Hill Notation):
C6H14N2O2 · HCl
CAS Number:
Molecular Weight:
182.65
Beilstein/REAXYS Number:
5460909
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

form

liquid

analyte chemical class(es)

amino acids, peptides, proteins

concentration

100 mM amino acid in 0.1 M HCl

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

colorless

application(s)

food and beverages

format

single component solution

storage temp.

2-8°C

SMILES string

Cl.NCCCC[C@H](N)C(O)=O

InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

InChI key

BVHLGVCQOALMSV-JEDNCBNOSA-N

General description

L-Lysine hydrochloride is one of the essential amino acids which usually finds applications in the treatment of shingles and genital as well mouth lesions attributed to herpes zoster and herpes simplex virus, respectively.

Application

L-Lysine hydrochloride may be used as a reference standard for the determination of L-lysine hydrochloride in pharmaceutical dosage form by high resolution high performance liquid chromatography (HR-HPLC). It may be used as a precursor of lysine for its determination in breath condensate by isotope dilution hydrophilic-interaction liquid chromatography combined with tandem mass spectrometry (HILIC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8B - Non-combustible, corrosive hazardous materials

wgk_germany

nwg

ppe

Eyeshields, Gloves


Certificates of Analysis (COA)

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Development and validation of new hplc method for simultaneous estimation of L-lysine hydrochloride and L-carnitine-L-tartrate in pharmaceutical dosage form.
Qadir MA, et al.
Indian Journal of Pharmaceutical Sciences, 77(4), 434-434 (2015)
Simultaneous determination of the advanced glycation end product Nε-carboxymethyllysine and its precursor, lysine, in exhaled breath condensate using isotope-dilution-hydrophilic-interaction liquid chromatography coupled to tandem mass spectrometry
Schettgen T, et al.
Analytical and Bioanalytical Chemistry, 387(8), 2783-2791 (2007)
Guntur Fibriansah et al.
Nature communications, 6, 6341-6341 (2015-02-24)
Dengue virus (DENV) infects ~400 million people annually. There is no licensed vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a naturally occurring dengue infection consists of highly neutralizing antibodies. Here we show that
Anne M Muskalla et al.
Clinical chemistry, 60(12), 1543-1548 (2014-10-11)
G-protein receptor kinase 4 polymorphism influences blood pressure regulation via modulation of dopamine receptor D1 in renal proximal tubular cells. We investigated the role of G-protein receptor kinase 4 polymorphism in the response to hypertensive therapy in patients with essential
Jing Li et al.
American journal of physiology. Cell physiology, 306(10), C943-C960 (2014-03-22)
The human solute carrier (SLC26) family of anion transporters consists of 10 members (SLCA1-11, SLCA10 being a pseudogene) that encode membrane proteins containing ~12 transmembrane (TM) segments with putative N-glycosylation sites (-NXS/T-) in extracellular loops and a COOH-terminal cytosolic STAS

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