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L5626

Sigma-Aldrich

L-Lysine monohydrochloride

reagent grade, ≥98% (HPLC)

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Synonym(s):
(S)-2,6-Diaminohexanoic acid monohydrochloride
Linear Formula:
H2N(CH2)4CH(NH2)CO2H·HCl
CAS Number:
Molecular Weight:
182.65
Beilstein/REAXYS Number:
3563889
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

grade

reagent grade

Quality Level

assay

≥98% (HPLC)

form

powder

technique(s)

immunohistochemistry: suitable

color

white to off-white

mp

263 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

OC([C@@H](N)CCCCN)=O.[H]Cl

InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

InChI key

BVHLGVCQOALMSV-JEDNCBNOSA-N

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This Item
PHR11016292967448
L-Lysine monohydrochloride reagent grade, ≥98% (HPLC)

L5626

L-Lysine monohydrochloride

Essential Grade
L-Lysine monohydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

PHR1101

L-Lysine monohydrochloride

-
L-Lysine monohydrochloride BioUltra, ≥99.5% (AT)

62929

L-Lysine monohydrochloride

Premium Grade
L-Lysine monohydrochloride certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

67448

L-Lysine monohydrochloride

-
grade

reagent grade

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

certified reference material, TraceCERT®

technique(s)

immunohistochemistry: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

assay

≥98% (HPLC)

assay

-

assay

≥99.5% (AT)

assay

-

color

white to off-white

color

-

color

white

color

white

mp

263 °C (dec.) (lit.)

mp

263 °C (dec.) (lit.)

mp

263 °C (dec.) (lit.)

mp

263 °C (dec.) (lit.)

Application

L-lysine monohydrochloride has been used:
  • as a component in pre-fixative solution for electron microscopy
  • as a component in blocking solution for immunohistochemistry(IHC)
  • in the preparation of Periodate-lysine-paraformaldehyde (PLP) fixative for IHC

Biochem/physiol Actions

L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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L-Lysine hydrochloride United States Pharmacopeia (USP) Reference Standard

USP

1372005

L-Lysine hydrochloride

L-Lysine monohydrochloride EMPROVE® EXPERT, Ph. Eur., BP, JP, USP

SAFC

1.05701

L-Lysine monohydrochloride

Arginine and lysine reduce the high viscosity of serum albumin solutions for pharmaceutical injection
Inoue N, et al.
Journal of Bioscience and Bioengineering, 117(5), 539-543 (2014)
Isolates with low-level vancomycin resistance associated with persistent methicillin-resistant Staphylococcus aureus bacteremia
Howden BP, et al.
Antimicrobial Agents and Chemotherapy, 50(9), 3039-3047 (2006)
Medicinal uses of L-Lysine: Past and future
Singh M, et al.
International Journal of Research in Pharmaceutical Sciences, 2(4), 637-642 (2016)
Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans
Smriga M, et al.
Biomedical Research, 28(2), 85-90 (2007)
Multispectral imaging of T and B cells in murine spleen and tumor
Feng Z, et al.
Journal of Immunology, 1502635-1502635 (2016)

Protocols

Enzymatic Assay of Plasmin with D-Val-Leu-Lys-p-Nitroanilide Dihydrochloride

Enzymatic Assay of Plasmin with D-Val-Leu-Lys-p-Nitroanilide Dihydrochloride

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