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H8125

Sigma-Aldrich

L-Histidine monohydrochloride monohydrate

≥98% (HPLC)

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Synonym(s):
L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride
Empirical Formula (Hill Notation):
C6H9N3O2 · HCl · H2O
CAS Number:
5934-29-2
Molecular Weight:
209.63
Beilstein:
4168261
MDL number:
MFCD00151027
eCl@ss:
32160406
PubChem Substance ID:
57654272
NACRES:
NA.32

Quality Level

200

Assay

≥98% (HPLC)

mp

254 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless to very faintly yellow

SMILES string

O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1

InChI key

CMXXUDSWGMGYLZ-XRIGFGBMSA-N

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This Item
H5659533701308550
L-Histidine monohydrochloride monohydrate ≥98% (HPLC)

Sigma-Aldrich

H8125

L-Histidine monohydrochloride monohydrate

L-Histidine monohydrochloride monohydrate from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

H5659

L-Histidine monohydrochloride monohydrate

L-Histidine monohydrochloride monohydrate ≥99.0% (AT)

Sigma-Aldrich

53370

L-Histidine monohydrochloride monohydrate

L-Histidine monohydrochloride monohydrate United States Pharmacopeia (USP) Reference Standard

USP

1308550

L-Histidine monohydrochloride monohydrate

solubility

H2O: 50 mg/mL, clear, colorless to very faintly yellow

solubility

H2O: 100 mg/mL

solubility

H2O: 1 g/10 mL, clear, colorless (hot)

solubility

-

mp

254 °C (dec.) (lit.)

mp

254 °C (dec.) (lit.)

mp

254 °C (dec.) (lit.)

mp

254 °C (dec.) (lit.)

Application

L-Histidine monohydrochloride monohydrate has been used as a component of broth to match the tuna meat amino acid composition. It has also been used for partial rescue of the IMPL2 (myo-inositol monophosphatase) phenotype during seed development of Arabidopsis.

Biochem/physiol Actions

Histidine takes part in protein methylation. It is associated with the hemoglobin structure and function. Histidine is present in antioxidative dipeptides. It is involved in one-carbon unit metabolism.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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MMYOMAG-74K-13

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L-Histidine

Modelling the effect of temperature, carbon dioxide, water activity and pH on growth and histamine formation by Morganella psychrotolerans
Emborg J and Dalgaard P
International Journal of Food Microbiology, 128(2), 226-233 (2008)
Yuko Sato et al.
Journal of plant research, 124(3), 385-394 (2010-10-21)
Myo-inositol monophosphatase (IMP) catalyzes the dephosphorylation of myo-inositol 3-phosphate in the last step of myo-inositol biosynthesis. IMP is also important in phosphate metabolism and is required for the biosynthesis of cell wall polysaccharides, phytic acid, and phosphatidylinositol. In Arabidopsis, IMP
Expression and functions of myo-inositol monophosphatase family genes in seed development of Arabidopsis
Sato Y, et al.
Journal of Plant Research, 124(3), 385-394 (2011)
Kiana Khadem-Abbassi et al.
Nanomaterials (Basel, Switzerland), 9(5) (2019-05-07)
This work describes the preparation of molecularly imprinted polymer (MIP)-modified core/shell CdTe0.5S0.5/ZnS quantum dots (QDs). The QDs@MIP particles were used for the selective and sensitive detection of dopamine (DA). Acrylamide, which is able to form hydrogen bonds with DA, and
A Bennett et al.
The Journal of nutrition, 129(12), 2236-2238 (1999-11-26)
Boron is required for the growth of vascular plants and embryonic development in fish. The molecular basis of boron's essentiality, however, remains unknown for both. The objective of this study was to determine whether yeast (Saccharomyces cerevisiae) could be used
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