Skip to Content
MilliporeSigma
All Photos(6)

Key Documents

M9625

Sigma-Aldrich

L-Methionine

≥98% (HPLC)

Synonym(s):

(S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3SCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
149.21
Beilstein/REAXYS Number:
1722294
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product name

L-Methionine, reagent grade, ≥98% (HPLC)

grade

reagent grade

Quality Level

assay

≥98% (HPLC)

form

powder

color

white

mp

284 °C (dec.) (lit.)

application(s)

detection

SMILES string

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

Gene Information

Looking for similar products? Visit Product Comparison Guide

Application

L-Methionine has been used in chloramine assay and malonaldehyde assay. It has also been used as a standard in methionine assay.

Biochem/physiol Actions

L-Methionine serves as precursor for transmethylation and transsulphuration. Methionine adenosylation results in the formation of S-adenosyl-L-methionine (SAM). SAM serves as a methyl donor to a number of substances. This methylation is significantly associated with the immune system functioning. Thus, SAM deficiency causes severe combined immunodeficiencies. L-Methionine′s metabolic product, glutathione, is known to regulate immune response and has antiviral action.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hypochlorite scavenging activity of hydroxycinnamic acids evaluated by a rapid microplate method based on the measurement of chloramines.
Firuzi O
The Journal of Pharmacy and Pharmacology, 55(7), 1021-1027 (2003)
The effects of processing methods on the levels of lysine, methionine and the general acceptability of ogi processed using starter cultures
O.D.Teniola and S.A.Odunfa
International Journal of Food Microbiology, 63(1), 1-9 (2001)
L-methionine as immune supportive supplement: a clinical evaluation
R. Van BrummelenD. du Toit
Amino Acids (2006)
Ronald O Ball et al.
The Journal of nutrition, 136(6 Suppl), 1682S-1693S (2006-05-17)
Sulfur amino acid metabolism has been receiving increased attention because of the link to chronic diseases such as cardiovascular disease, Alzheimer's disease, and diabetes. In addition, the role of cysteine and optimal intakes for physiological substrates such as glutathione are
Eline van Meel et al.
BMC medical genetics, 14, 106-106 (2013-10-10)
Methionyl-tRNA synthetase (MARS) catalyzes the ligation of methionine to its cognate transfer RNA and therefore plays an essential role in protein biosynthesis. We used exome sequencing, aminoacylation assays, homology modeling, and immuno-isolation of transfected MARS to identify and characterize mutations

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service