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M9625

Sigma-Aldrich

L-Methionine

reagent grade, ≥98% (HPLC)

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Synonym(s):
(S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid
Linear Formula:
CH3SCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
149.21
Beilstein/REAXYS Number:
1722294
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

grade

reagent grade

Quality Level

assay

≥98% (HPLC)

form

powder

color

white

mp

284 °C (dec.) (lit.)

application(s)

detection

SMILES string

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

Gene Information

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1 of 4

This Item
6431939496M8439
L-Methionine reagent grade, ≥98% (HPLC)

M9625

L-Methionine

Essential Grade
L-Methionine BioUltra, ≥99.5% (NT)

64319

L-Methionine

Premium Grade
L-Methionine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

39496

L-Methionine

-
L-Methionine

M8439

L-Methionine

-
form

powder

form

powder or crystals

form

-

form

powder

assay

≥98% (HPLC)

assay

≥99.5% (NT)

assay

-

assay

≥99%

mp

284 °C (dec.) (lit.)

mp

284 °C (dec.) (lit.)

mp

284 °C (dec.) (lit.)

mp

284 °C (dec.) (lit.)

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

400

color

white

color

white

color

white

color

-

Application

L-Methionine has been used in chloramine assay and malonaldehyde assay. It has also been used as a standard in methionine assay.

Biochem/physiol Actions

L-Methionine serves as precursor for transmethylation and transsulphuration. Methionine adenosylation results in the formation of S-adenosyl-L-methionine (SAM). SAM serves as a methyl donor to a number of substances. This methylation is significantly associated with the immune system functioning. Thus, SAM deficiency causes severe combined immunodeficiencies. L-Methionine′s metabolic product, glutathione, is known to regulate immune response and has antiviral action.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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L-methionine as immune supportive supplement: a clinical evaluation
R. Van BrummelenD. du Toit
Amino Acids (2006)
Hypochlorite scavenging activity of hydroxycinnamic acids evaluated by a rapid microplate method based on the measurement of chloramines.
Firuzi O
The Journal of Pharmacy and Pharmacology, 55(7), 1021-1027 (2003)
The effects of processing methods on the levels of lysine, methionine and the general acceptability of ogi processed using starter cultures
O.D.Teniola and S.A.Odunfa
International Journal of Food Microbiology, 63(1), 1-9 (2001)
Ronald O Ball et al.
The Journal of nutrition, 136(6 Suppl), 1682S-1693S (2006-05-17)
Sulfur amino acid metabolism has been receiving increased attention because of the link to chronic diseases such as cardiovascular disease, Alzheimer's disease, and diabetes. In addition, the role of cysteine and optimal intakes for physiological substrates such as glutathione are
B Almé et al.
Journal of lipid research, 18(3), 339-362 (1977-05-01)
A method is described for quantitative analysis of bile acids in urine. Urine is acidified and bile acids are extracted on an Amberlite XAD-2 column. Bile salts are converted to acids on an Amberlyst A-15 column and are separated into

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