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S4500

Sigma-Aldrich

L-Serine

ReagentPlus®, ≥99% (HPLC)

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Synonym(s):
(S)-2-Amino-3-hydroxypropionic acid
Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
105.09
Beilstein:
1721404
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product line

ReagentPlus®

Assay

≥99% (HPLC)

form

powder

color

white to off-white

mp

222 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

application(s)

detection

storage temp.

room temp

SMILES string

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

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1 of 4

This Item
84959S4311PHR1103
L-Serine ReagentPlus®, ≥99% (HPLC)

Sigma-Aldrich

S4500

L-Serine

-
L-Serine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

84959

L-Serine

Premium Grade
L-Serine from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

S4311

L-Serine

-
L-Serine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1103

L-Serine

-
assay

≥99% (HPLC)

assay

≥99.5% (NT)

assay

98.5-101.0%

assay

-

form

powder

form

powder or crystals

form

powder

form

-

color

white to off-white

color

white

color

white

color

-

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

solubility

1 M HCl: 0.5 M at 20 °C, clear, colorless

solubility

H2O: 50 mg/mL

solubility

-

Application

L-Serine has been used in the preparation of Tris-BSAN buffer for homogenization. It has also been used for quantitative analysis of excretion of polypeptides in normal urine.

Biochem/physiol Actions

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system. L-Serine also has a role in cellular proliferation.
Precursor of glycine by serine hydroxymethyltransferase.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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Taiga Okumura et al.
Scientific reports, 9(1), 3520-3520 (2019-03-07)
Radiocaesium-bearing microparticles (CsMPs) composed of silicate glass were released by the Fukushima Daiichi Nuclear Power Plant accident in March 2011. Since CsMPs contain a high concentration of radiocaesium, their dynamics and fate in the environment are urgent issues to be
Analysis of GSH and GSSG after derivatization with N-ethylmaleimide
Nature Protocols, 8(9) (2003)
L-Serine in disease and development
Tom J. de Koning
Biochemistry, 371 (2003)
Taiga Okumura et al.
Scientific reports, 8(1), 9707-9707 (2018-06-28)
Radiocesium-bearing microparticles (CsPs) substantially made of silicate glass are a novel form of radiocesium emitted from the broken containment vessel of Fukushima Dai-ichi nuclear power plant. CsPs have a potential risk of internal radiation exposure caused by inhalation. Radiation-contaminated waste
Quantitative amino acid and proteomic analysis: Very low excretion of polypeptides >750 Da in normal urine
Anthony G.W.Norden
Kidney International, 66(5) (2004)

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