MilliporeSigma
All Photos(2)

Documents

49777

Supelco

Neotame

analytical standard

Sign Into View Organizational & Contract Pricing

Synonym(s):
N-[N-(3,3-Dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
Empirical Formula (Hill Notation):
C20H30N2O5
CAS Number:
Molecular Weight:
378.46
Beilstein:
8352678
MDL number:
PubChem Substance ID:
E Number:
E961
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (HPLC)

optical activity

[α]/D -41.0±3.0°, c = 0.5 in H2O

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NCCC(C)(C)C

InChI

1S/C20H30N2O5/c1-20(2,3)10-11-21-15(13-17(23)24)18(25)22-16(19(26)27-4)12-14-8-6-5-7-9-14/h5-9,15-16,21H,10-13H2,1-4H3,(H,22,25)(H,23,24)/t15-,16-/m0/s1

InChI key

HLIAVLHNDJUHFG-HOTGVXAUSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
PHR1698PHR13811460204
Neotame analytical standard

Supelco

49777

Neotame

Supelco

Supelco

PHR1698

Neotame

Aspartame Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1381

Aspartame

USP

USP

1460204

Neotame

assay

≥98.0% (HPLC)

assay

-

assay

-

assay

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

General description

Neotame is a white colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in variety of foods. It is manufactured from aspartame and 3,3-dimethylbutyraldehyde in a one-step chemical synthesis process.
Neotame is chemically related to aspartame, an artificial sweetener, used in the production of sugar-free low-calorie foodstuffs. It is approved as a food additive depending upon the food or beverage application.

Application

Neotame may be used as an analytical reference standard for the quantification of the analyte in the following:
  • Wine samples using reversed-phase high-performance liquid chromatography (RP-HPLC).
  • Wastewaters using hydrophilic interaction liquid chromatography (HILIC).
  • Food samples using high-performance liquid chromatography (HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 7

1 of 7

Sodium Saccharin analytical standard

Supelco

47839

Sodium Saccharin

Acesulfame K for food analysis, ≥99.0%

Supelco

04054

Acesulfame K

Sucralose ≥98.0% (HPLC)

Sigma-Aldrich

69293

Sucralose

Saccharin ≥99%

Sigma-Aldrich

240931

Saccharin

Glycyrrhizic Acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1516

Glycyrrhizic Acid

Neotame: discovery, properties, utility
Nofre C and Tinti M-J
Food Chemistry, 69, 245-257 (2000)
Modifying the temporal profile of the high-potency sweetener neotame
Prakash I, et al.
Journal of Agricultural and Food Chemistry, 49, 786-789 (2001)
Joint RAO/WHO Expert Committee on Food Additives, World Health Organization
Evaluation of Certain Food Additives: Seventy-first Report of the Joint FAO/WHO Expert Committee on Food Additives (2004)
Determination of nine high-intensity sweeteners in various foods by high-performance liquid chromatography with mass spectrometric detection
Zygler A, et al.
Analytical and Bioanalytical Chemistry, 400(07), 2159-2172 (2011)
Neotame as a sweetener and flavour enhancer?Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
European Food Safety Authority (EFSA)
EFSA Journal, 5(11), 581-581 (2007)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service