Skip to Content
MilliporeSigma
All Photos(1)

Documents

67028

Sigma-Aldrich

Methylglyoxal solution

technical, ~40% in H2O

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
Acetylformaldehyde, Pyruvaldehyde, Pyruvic aldehyde
Linear Formula:
CH3COCHO
CAS Number:
78-98-8
Molecular Weight:
72.06
Beilstein/REAXYS Number:
906750
MDL number:
MFCD00006960
UNSPSC Code:
12352100
PubChem Substance ID:
329760261
NACRES:
NA.22

grade

technical

Quality Level

200

concentration

~40% in H2O

density

1.19 g/mL at 20 °C

storage temp.

2-8°C

SMILES string

[H]C(=O)C(C)=O

InChI

1S/C3H4O2/c1-3(5)2-4/h2H,1H3

InChI key

AIJULSRZWUXGPQ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Methylglyoxal is a toxic endogenous by-product of glycolysis. It is a reactive dicarbonyl compound that promotes non-enzymatic glycation of proteins to yield irreversible advanced glycated end products, leading to the cross-linking or degradation of proteins.

Application

Methylglyoxal solution is used in cytotoxic studies.

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Sens. 1

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 8

1 of 8

USP

USP

1204102

Dihydroxyacetone

Dihydroxyacetone for synthesis

Sigma-Aldrich

8.20482

Dihydroxyacetone

(R)-3-Hydroxybutyric acid ≥98.0% (T)

Sigma-Aldrich

54920

(R)-3-Hydroxybutyric acid

(±)-Sodium 3-hydroxybutyrate ≥99.0% (NT)

Sigma-Aldrich

54965

(±)-Sodium 3-hydroxybutyrate

Phenylglyoxal hydrate 97%

Sigma-Aldrich

142433

Phenylglyoxal hydrate

Sigma-Aldrich

Sigma-Aldrich

A8301

Albumin, glycated human

Hydroxyacetone contains ≤500 ppm sodium carbonate as stabilizer, technical grade, 90%

Sigma-Aldrich

138185

Hydroxyacetone

2,3-Butanedione analytical standard

Supelco

11038

2,3-Butanedione

Potential Neuroprotective and Anti-Apoptotic Properties of a Long-Lasting Stable Analog of Ghrelin: an In Vitro Study Using SH-SY5Y Cells.
Popelova A, et al.
Physiological Research, 67(2), 339-346 (2018)
Determination of methylglyoxal in human blood plasma using fluorescence high performance liquid chromatography after derivatization with 1, 2-diamino-4, 5-methylenedioxybenzene.
Ogasawara Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1029, 102-105 (2016)
Computational and experimental exploration of the structure?activity relationships of flavonoids as potent glyoxalase?I inhibitors.
Al?Balas Q A, et al.
Drug Development Research, 79(2), 58-69 (2018)
Nicole Schupp et al.
Annals of the New York Academy of Sciences, 1043, 685-695 (2005-07-23)
In patients with chronic renal failure, cancer incidence is increased. This may be related to an elevated level of genomic damage, which has been demonstrated by micronuclei formation as well as by comet assay analysis. Advanced glycation end products (AGEs)
Naila Ahmed et al.
Investigative ophthalmology & visual science, 44(12), 5287-5292 (2003-11-26)
To determine the concentrations of methylglyoxal-derived advanced glycation end-products (AGEs), the hydroimidazolones MG-H1 and -H2, in soluble human lens proteins and compare them with the concentrations of other methylglyoxal-derived AGEs and pentosidine. Lens protein samples were hydrolyzed enzymatically. AGEs were
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service