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69732

Millipore

Lithium mupirocin Supplement

suitable for microbiology,

Selectively inhibits the growth of lactic acid bacteria

Synonym(s):
Lithium mupirocin solution, Li-MUP, MUP supplement
Empirical Formula (Hill Notation):
C26H43LiO9
CAS Number:
Molecular Weight:
506.56
MDL number:
PubChem Substance ID:
NACRES:
NA.85

Agency

ISO 29981:2010

Quality Level

sterility

sterile (Filtered and Aseptic Handled)
sterile

form

liquid

shelf life

limited shelf life, expiry date on the label

application(s)

environmental
food and beverages

microbiology

storage temp.

2-8°C

suitability

Lactobacillus spp.
Lactococcus spp.
Leuconostoc spp.
Streptococcus spp.

SMILES string

[Li+].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]2CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]2O

InChI

1S/C26H44O9.Li/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);/q;+1/p-1/b16-13+;/t17-,18-,19-,20-,21-,24+,25-,26-;/m0./s1

InChI key

XFIKMPRBSORKQP-JATHGWPISA-M

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This Item
PHR34211448923M3806000
Mupirocin Lithium certified reference material, pharmaceutical secondary standard

Supelco

PHR3421

Mupirocin Lithium

Mupirocin lithium United States Pharmacopeia (USP) Reference Standard

USP

1448923

Mupirocin lithium

Mupirocin lithium European Pharmacopoeia (EP) Reference Standard

M3806000

Mupirocin lithium

form

liquid

form

-

form

-

form

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

application(s)

environmental
food and beverages, microbiology

application(s)

pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

storage temp.

-10 to -25°C

storage temp.

-

storage temp.

2-8°C

suitability

Lactobacillus spp., Lactococcus spp., Leuconostoc spp., Streptococcus spp.

suitability

-

suitability

-

suitability

-

General description

Lithium mupirocin is isolated from Pseudomonas fluorescens. At lower concentrations, it has bacteriostatic characteristics, while at higher concentrations it is bacteriocidal. Mupirocin is active against gram-positive bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA), Lactobacilli, Lactococci, Streptococci and Leuconostocs. Mupirocin has been used to study mupirocin resistance in Mycoplasma bacteria. Mupirocin inhibits the isoleucyl-tRNA synthetase, which finally results in inhibition of protein and RNA synthesis. Mupirocin lithium salt is freely soluble in water.

Application

Lithium mupirocin supplement is used for selective enumeration of Bifidobacteria from fermented milk products along with the TOS-propionate agar according to ISO 29981:2010 and IDF 220:2010

Components

Composition:
(5ml, sufficient for 100 ml medium)
Mupirocin 5 mg
sterile distilled water 5.0 ml

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Variation, viability and validity of bifidobacteria in fermented milk products.
Raeisi, Shahram Naghizadeh, et al.
Food Control, 34, 691-697 (2013)
J Gilbart et al.
Antimicrobial agents and chemotherapy, 37(1), 32-38 (1993-01-01)
Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four
Emergence of methicillin-resistant Staphylococcus aureus ST239 with high-level mupirocin and inducible clindamycin resistance in a tertiary care center in Chennai, South India.
Nagarajan Abimanyu et al.
Journal of clinical microbiology, 50(10), 3412-3413 (2012-08-03)
Yi-Yuan Chiu et al.
BMC genomics, 13 Suppl 7, S21-S21 (2013-01-11)
To discover a compound inhibiting multiple proteins (i.e. polypharmacological targets) is a new paradigm for the complex diseases (e.g. cancers and diabetes). In general, the polypharmacological proteins often share similar local binding environments and motifs. As the exponential growth of
Tomás García-Lozano et al.
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 25(4), 252-255 (2013-01-11)
Our objective was to determine the prevalence of methicillin-resistant Staphylococcus aureus in workers who had direct contact with oncologic patients infected with MRSA and admitted to the intensive care unit of the Valencian Institute of Oncology. A study of prevalence

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