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80645

Sigma-Aldrich

Piperidine solution

suitable for peptide synthesis, 20% in DMF

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Synonym(s):
Azacyclohexane, Cyclopentimine, Hexahydropyridine, Pentamethyleneimine
Empirical Formula (Hill Notation):
C5H11N
CAS Number:
Molecular Weight:
85.15
Beilstein:
1421082
MDL number:
PubChem Substance ID:
NACRES:
NA.31

form

liquid

Quality Level

concentration

20% in DMF

impurities

≤0.1% water

refractive index

n20/D 1.434

density

0.930 g/mL at 20 °C

application(s)

peptide synthesis

SMILES string

C1CCNCC1

InChI

1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2

Inchi Key

NQRYJNQNLNOLGT-UHFFFAOYSA-N

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1 of 4

This Item
411027PX12351.09724
Piperidine solution suitable for peptide synthesis, 20% in DMF

Sigma-Aldrich

80645

Piperidine solution

Piperidine ≥99.5%, purified by redistillation

Sigma-Aldrich

411027

Piperidine

Piperidine

Supelco

PX1235

Piperidine

Piperidine for analysis EMSURE®

Supelco

1.09724

Piperidine

refractive index

n20/D 1.434

refractive index

n20/D 1.452 (lit.)

refractive index

-

refractive index

-

density

0.930 g/mL at 20 °C

density

0.862 g/mL at 20 °C (lit.)

density

0.86 g/cm3 at 20 °C

density

0.86 g/cm3 at 20 °C

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

300

concentration

20% in DMF

concentration

-

concentration

-

concentration

-

impurities

≤0.1% water

impurities

-

impurities

≤0.2% Water (H2O)

impurities

≤0.0001% Fe (Iron), ≤0.0001% Heavy metals (as Pb), ≤0.20% Picoline (GC), ≤0.3% Water (Karl Fischer), ≤0.30% Pyridine (GC)

Other Notes

Sales restrictions may apply

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

82.4 °F - closed cup

Flash Point(C)

28 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Journal of materials chemistry. B, 8(47), 10825-10836 (2020-11-12)
Cell-penetrating peptides are a promising therapeutic strategy for a wide variety of degenerative diseases, ageing, and cancer. Among the multitude of cell-penetrating peptides, PepFect14 has been preferentially used in our laboratory for oligonucleotide delivery into cells and in vivo mouse
Xuwang Chen et al.
Bioorganic & medicinal chemistry, 20(12), 3856-3864 (2012-05-18)
A novel series of piperidine-linked amino-triazine derivatives were designed, synthesized and evaluated for in vitro anti-HIV activity as non-nucleoside reverse transcriptase inhibitors on the basis of our previous work. Screening results indicated that most compounds showed excellent activity against wild-type
P Ricardo Girling et al.
Organic & biomolecular chemistry, 9(9), 3105-3121 (2011-03-11)
A review into the aza-Diels-Alder reaction, mainly concentrating on literature examples that form piperidin-4-ones from the reaction of imines and electron rich dienes or enones, either through a Lewis acidic/Brønsted acid approach or through the use of an organocatalyst. This
Total synthesis of (-)-kopsinine by an asymmetric one-pot [n+2+3] cyclization.
Shingo Harada et al.
Chemistry, an Asian journal, 7(10), 2196-2198 (2012-08-22)
Elisabeth T Hennessy et al.
Science (New York, N.Y.), 340(6132), 591-595 (2013-05-04)
The manipulation of traditionally unreactive functional groups is of paramount importance in modern chemical synthesis. We have developed an iron-dipyrrinato catalyst that leverages the reactivity of iron-borne metal-ligand multiple bonds to promote the direct amination of aliphatic C-H bonds. Exposure

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KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.

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