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91274

Millipore

Penicillinase Concentrate

suitable for (Antibiotic inactivation), vial of 100 mL

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Synonym(s):
Penicillinase solution, β-Lactamase I, β-Lactamase I concentrate, Penicillinase enzyme
CAS Number:

form

liquid

Quality Level

shelf life

limited shelf life, expiry date on the label

packaging

vial of 100 mL

suitability

suitable for (Antibiotic inactivation)

application(s)

microbiology

storage temp.

2-8°C

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Millipore

91274

Penicillinase Concentrate

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Sigma-Aldrich

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β-Lactamase

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Penicillinase from Bacillus cereus lyophilized powder, 1,500-3,000 units/mg protein (using benzylpenicillin)

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Citrate Concentrated Solution BioReagent, suitable for coagulation assays, 4 % (w/v)

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Citrate Concentrated Solution

Essential+ Grade
Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

packaging

vial of 100 mL

packaging

-

packaging

-

packaging

-

suitability

suitable for (Antibiotic inactivation)

suitability

-

suitability

-

suitability

suitable for coagulation assays

General description

Penicillinase Concentrate is a highly purified enzyme preparation that contains β-Lactamase, which is also known as penicillinase. It is a ready-to-use solution that can be directly added to test samples (for the inactivation of beta-lactams from blood or tissue samples before routine microbiological examination) or can be used in media preparation (for either environmental monitoring or antibiotic sterility testing). This concentrate is specifically designed for use in microbiology as a supplement to culture media to deactivate antibiotics in microbial samples. It can inactivate Penicillin G, one of the commonly used Penicillin, at an impressive rate of 10,000,000 International Units (IU) per mL per minute.

Penicillinase Concentrate is a valuable tool for hydrolyzing and inactivating the β-lactam ring found in penicillin and other related antibiotics. It plays a critical role in studying antibiotic resistance mechanisms and in the development of antibiotic detection assays.

Application

PenicillinaseConcentrate is a culture media supplement used for the deactivation of antibioticsin microbial samples.


Inactivation of Penicillin G* 10,000,000 IU/mL/min


*Not all penicillins are comparable to Penicillin G in regards to their inactivation by penicillinase. Some may require as much as 20 times more penicillinase than does Penicillin G


Potency** 20,000 Levy units/ml/min


**Levy Unit (LU): amount of penicillinase that inactivates 59.3 IU( International Units) of Sodium Penicillin G per minute at 25°C and pH 7.0

Packaging

100 ml per vial

Components

Composition:
(100 ml per vial)

Inactivation of Penicillin G* 10,000,000 IU/mL/min
*Not all penicillins are comparable to Penicillin G in regards to their inactivation by penicillinase. Some may require as much as 20 times more penicillinase than does Penicillin G.

Potency** 20,000 Levy units/ml/min
**Levy Unit (LU): amount of penicillinase that inactivates 59.3 IU( International Units) of Sodium Penicillin G per minute at 25°C and pH 7.0

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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