91719

Trifluoroacetic anhydride

for GC derivatization, LiChropur^™, ≥99.0% (GC)

• Synonym(s): TFAA
• Linear Formula: (CF₃CO)₂O
• CAS Number: 407-25-0
• Molecular Weight: 210.03
• Beilstein/REAXYS Number: 746197
• EC Number: 206-982-9
• MDL number: MFCD00000416
• UNSPSC Code: 12000000
• PubChem Substance ID: 329770069
• NACRES: NA.22

Properties

• grade: for GC derivatization
• Quality Level: 100
• vapor pressure: 6.28 psi ( 20 °C)
• assay: ≥99.0% (GC)
• form: liquid
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Esterifications
• technique(s): gas chromatography (GC): suitable (ECD)
• refractive index: n20/D 1.3 (lit.)
• bp: 39.5-40 °C (lit.)
• mp: −65 °C (lit.)
• density: 1.511 g/mL at 20 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)C(=O)OC(=O)C(F)(F)F
• InChI: 1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10
• InChI key: QAEDZJGFFMLHHQ-UHFFFAOYSA-N

Description

Application

Learn more in the Product Information

Suitable for derivatization of amines, aryl amines, phenolic amines, primany amines, tertiary aromatic amines, amino acids, aminoalkylphosphoric acids, 2-aminoethylphosphoric acid, 1-hydroxy-2-aminoethylphosponic acid, amphetamine, beta blocker drugs, creatinine, desipramine, dopamine, glutathione, glycol (MOPEG), guanidine drugs, histidine, n-hydroxy-2-fluorenylacetamide, n-hydroxylamines, hydroxy acids, p-hydroxyamphetamine, 4-hydroxycoumarins, p-hydroxynorephedrine, hydroxysteroids, 5-hydroxytryptamine, indoles, Iodoamino acids, carbaryl and hydroxylated metabolites, metanephrine, methylphenidate, norepinephrine, normetanephrine, peptide amide, phenformin, phenols, phentermine, phenylthiohydantoin amino acid, propranolol, sulfonamides, sulfonylureas, thiamine, vanillymandelic acid, trisubstituted ureas and urea.

Other Notes

For the protection of prim. and sec. amines; derivatives are more volatile

Reagent for cabethoxy, butyl ester, n-methyl, methyl ester, di(trifluoroacetyl), hexafluoroisopropyl ester, acetyl or trifluoroacetyl phenylthihydantoins, trifluoroacetyl (2-hydroxy-2-methyl)ethyl, n-trifluoroacetyl, trifluoroacetyl (TFA), trifluoroacetamide, 4-trifluoromethyl-2, 6-diamino-1,3,5-triazineacetyl and trifluoroacetyl vanillin.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H314,H332,H412
• pcodes: P273 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
• supp_hazards: EUH014
• wgk_germany: WGK 2
• ppe: Faceshields, Gloves, Goggles