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PHR1093

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Sulfanilamide melting point standard

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Sulfanilamide, p-Aminobenzenesulfonamide
Linear Formula:
H2NC6H4SO2NH2
CAS Number:
Molecular Weight:
172.20
Beilstein/REAXYS Number:
511852
EC Number:
MDL number:
eCl@ss:
39093202
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1633007

API family

sulfanilamide

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

~Approximately 166 °C
164-166 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Nc1ccc(cc1)S(N)(=O)=O

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

InChI key

FDDDEECHVMSUSB-UHFFFAOYSA-N

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1 of 4

This Item
46874S92511633007
Sulfanilamide VETRANAL®, analytical standard

46874

Sulfanilamide

Sulfanilamide ≥98%

S9251

Sulfanilamide

application(s)

pharmaceutical (small molecule)

application(s)

clinical testing

application(s)

-

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

-

format

neat

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

-

grade

certified reference material, pharmaceutical secondary standard

grade

analytical standard

grade

-

grade

pharmaceutical primary standard

storage temp.

2-30°C

storage temp.

-

storage temp.

-

storage temp.

-

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfanilamide Melting Point Standard, also called Sulfanilamide, is an antibacterial drug. It blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Sulfanilamide Melting Point Standard also called Sulfanilamide is an antibacterial drug.

Application

It was used in a study to demonstrate photodecomposition in aqueous solution of cutaneous photosensitizing agents with the help of spin traps 5, 5-dimethyl-1-pyrroline-1-oxide.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB1410 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS?II. SPIN TRAPPING OF PHOTOLYSIS PRODUCTS FROM SULFANILAMIDE AND 4-AMINOBENZOIC ACID USING 5, 5-DIMETHYL-1-PYRROLINE-1-OXIDE.
Chignell, Colin F., et al.
Photochemistry and Photobiology, 34.2 , 147-156 (1981)
Ramazan Demirdağ et al.
Bioorganic & medicinal chemistry, 21(6), 1522-1525 (2012-09-15)
Carbonic anhydrase (CA, EC: 4.2.1.1) was purified from sheep kidney by affinity chromatography on a Sepharose 4B-tyrosine-sulfanilamide column. By means of two consecutive procedures, the enzyme (sCA) was purified 227.61-fold with a yield of 60.75%, and a specific activity of
Fei Liu et al.
Organic letters, 12(4), 868-871 (2010-01-19)
The synthesis of benzofused sultams and/or fluorinated sulfonamides, starting from N-allylic sulfonamides, was performed in superacid HF/SbF(5), through superelectrophilic activation. A dramatic effect of superacid composition on the selectivity of the reaction was shown and applied to the synthesis of
Xian-Long Wang et al.
European journal of medicinal chemistry, 45(10), 4631-4639 (2010-08-17)
A series of novel sulfanilamide-derived 1,2,3-triazole compounds were synthesized in excellent yields via 1,3-dipolar cycloaddition and confirmed by MS, IR and NMR spectra as well as elemental analyses. All the compounds were screened in vitro for their antibacterial and antifungal
Penghua Wang et al.
Water research, 45(16), 5015-5026 (2011-08-02)
A novel carbon-sensitized and nitrogen-doped TiO2 (C/N-TiO2) was synthesized by a facile sol-gel method using titanium butoxide as both titanium precursor and carbon source, and nitric acid as nitrogen source. The calcination temperature had a great effect on the crystal

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