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PHR1115

Supelco

Stearyl Alcohol

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
1-Octadecanol, Octadecyl alcohol, Stearyl alcohol
Linear Formula:
CH3(CH2)17OH
CAS Number:
Molecular Weight:
270.49
Beilstein:
1362907
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to Ph. Eur. S1350000
traceable to USP 1622000

vapor density

9.3 (vs air)

vapor pressure

<0.01 mmHg ( 38 °C)

API family

stearyl alcohol

CofA

current certificate can be downloaded

autoignition temp.

842 °F

expl. lim.

~8 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

56-59 °C (lit.)

density

0.812 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCCCCCCO

InChI

1S/C18H38O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h19H,2-18H2,1H3

InChI key

GLDOVTGHNKAZLK-UHFFFAOYSA-N

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Stearyl Alcohol Pharmaceutical Secondary Standard; Certified Reference Material

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PHR1115

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Stearic Acid Pharmaceutical Secondary Standard; Certified Reference Material

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PHR1444

Sodium Stearyl Fumarate

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

General description

Stearyl Alcohol is added as a stiffening agent in cosmetics and pharmaceutical formulations. It is also utilized to enhance the water-holding capacity of ointments. Its other applications include the use in controlled-release tablets, suppositories, and microspheres.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Stearyl Alcohol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by gas chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7161 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

383.0 °F

Flash Point(C)

195 °C


Certificates of Analysis (COA)

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Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

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USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 40(2), 6072-6072 (2015)
Handbook of Pharmaceutical Excipients 6th edition Pharmaceutical Press (2009)
W B Rizzo et al.
The Journal of pediatrics, 115(2), 228-234 (1989-08-01)
We investigated fatty alcohol metabolism in eight patients with Sjögren-Larsson syndrome, and in nine obligate heterozygotes. Fatty alcohol: nicotinamide-adenine dinucleotide oxidoreductase (FAO) activity was deficient in cultured skin fibroblasts (mean 18% of normal, n = 8) and peripheral blood leukocytes
The oxorhenium(VII)-catalyzed direct condensation of phosphoric acid with an alcohol.
Akira Sakakura et al.
Angewandte Chemie (International ed. in English), 46(9), 1423-1426 (2007-01-18)
H O Ammar et al.
International journal of pharmaceutics, 327(1-2), 81-88 (2006-09-05)
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