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PHR1155

Supelco

Octyldodecanol

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
2-Octyl-1-dodecanol
Linear Formula:
CH3(CH2)9CH[(CH2)7CH3]CH2OH
CAS Number:
Molecular Weight:
298.55
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to Ph. Eur. O0101000
traceable to USP 1477808

API family

octyldodecanol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.453 (lit.)

bp

234-238 °C/33 mmHg (lit.)

mp

−1-1 °C (lit.)

density

0.838 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CCCCCCCCCCC(CO)CCCCCCCC

InChI

1S/C20H42O/c1-3-5-7-9-11-12-14-16-18-20(19-21)17-15-13-10-8-6-4-2/h20-21H,3-19H2,1-2H3

InChI key

LEACJMVNYZDSKR-UHFFFAOYSA-N

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vibrant-m

PHR1155

Octyldodecanol

vibrant-m

PHR1208

1-Propanol

vibrant-m

PHR1853

Tetrahydrozoline hydrochloride

vibrant-m

PHR1133

Cetyl Alcohol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Octyldodecanol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7139 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

370.4 °F - open cup

flash_point_c

188 °C - open cup


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Solvent effect on photostability of butyl methoxy di benzoyl methane formulated in solution and emulsion
DURANGO S, et al.
International Journal of Pharmacy and Pharmaceutical Sciences, 7(9), 181-186 (2015)
Selection of solubility parameters for characterization of pharmaceutical excipients
Adamska K, et al.
Journal of Chromatography A, 1171(1-2), 90-97 (2007)
Contact sensitivity to octyldodecanol and trometamol in an anti-itch cream.
M Singh et al.
Contact dermatitis, 56(5), 289-290 (2007-04-20)
Adriana Gámbaro et al.
Journal of cosmetic science, 57(6), 455-463 (2007-01-27)
Nine formulations to be used as stick bases were manufactured using sodium stearate, propyleneglycol, and water, adding different concentrations of the following conditioning agents: octyldodecanol, PPG-5-ceteth-20, and PPG-15-stearyl ether. Free-choice-profile methodology was used to select the most adequate concentration of
Ikuhiro Kakubari et al.
Biological & pharmaceutical bulletin, 29(8), 1717-1722 (2006-08-02)
Skin permeation of formoterol fumarate (FF) and irritation with ethylene-vinyl acetate (EVA) copolymer matrix patches was investigated using rat and human skin in vitro and different species of experimental animal, respectively. Skin permeation of FF increased remarkably without addition of

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