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PHR1266

Supelco

Acesulfame K

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Acesulfame potassium salt, 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium salt
Empirical Formula (Hill Notation):
C4H4KNO4S
CAS Number:
Molecular Weight:
201.24
Beilstein:
3637857
EC Number:
MDL number:
PubChem Substance ID:
E Number:
E950
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to Ph. Eur. A0070000
traceable to USP 1002505

API family

acesulfame

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

[K+].CC1=CC(=O)[N-]S(=O)(=O)O1

InChI

1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1

InChI key

WBZFUFAFFUEMEI-UHFFFAOYSA-M

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This Item
W700544040541002505
Acesulfame K Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1266

Acesulfame K

Acesulfame potassium ≥99%, FG

Sigma-Aldrich

W700544

Acesulfame potassium

Acesulfame K for food analysis, ≥99.0%

Supelco

04054

Acesulfame K

Acesulfame potassium United States Pharmacopeia (USP) Reference Standard

USP

1002505

Acesulfame potassium

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

application(s)

flavors and fragrances

application(s)

food and beverages

application(s)

pharmaceutical (small molecule)

format

neat

format

-

format

-

format

neat

storage temp.

2-30°C

storage temp.

-

storage temp.

-

storage temp.

-

Quality Level

300

Quality Level

400

Quality Level

100

Quality Level

-

General description

Acesulfame K is a synthetically prepared sulfonyl amide sweetener, widely used with sugar alcohols in food and beverage industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Acesulfame K may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using capillary zone electrophoresis and ion chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1663 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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-
25G
Pack Size/Quantity

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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

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Bitter taste receptors for saccharin and acesulfame K
The Journal of Neuroscience, 24(45), 10260-10265 (2004)
Simultaneous determination of artificial sweeteners, preservatives, caffeine, theobromine and theophylline in food and pharmaceutical preparations by ion chromatography
Chen C-Q and Wang J
Journal of Chromatography A, 937(1-2), 57-64 (2001)
Biotechnology and Food Ingredients (1991)
Wei-Li Li et al.
Journal of molecular neuroscience : MN, 51(1), 225-236 (2013-04-23)
The sweet taste is of immense interest to scientists and has been intensively studied during the last two decades. However, the sweet preference modification and the related mechanisms are still unclear. In this study, we try to establish a mice
Mi-Sun Ha et al.
International journal of food sciences and nutrition, 64(6), 715-723 (2013-05-02)
Using a stepwise assessment of the exposure of Korean consumers to acesulfame K and sucralose, theoretical maximum daily intakes of the sweeteners were calculated using the Budget screening method, which resulted in values greater than the acceptable daily intakes (ADIs).

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