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PHR1748

Supelco

Glacial Acetic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Acetic acid, Glacial acetic acid
Linear Formula:
CH3CO2H
CAS Number:
Molecular Weight:
60.05
Beilstein:
506007
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1005706

vapor density

2.07 (vs air)

API family

glacial acetic acid

CofA

current certificate can be downloaded

autoignition temp.

800 °F

expl. lim.

16 %, 92 °F
4 %, 59 °F

packaging

ampule of 3x1.5 mL

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.371 (lit.)

bp

117-118 °C (lit.)

mp

16.2 °C (lit.)

density

1.049 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CC(O)=O

InChI

1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

InChI key

QTBSBXVTEAMEQO-UHFFFAOYSA-N

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This Item
33209PHR1013PHR1427
Glacial Acetic Acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1748

Glacial Acetic Acid

-
Acetic acid glacial, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.8%

Sigma-Aldrich

33209

Acetic acid

Essential Grade
Salicylic acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1013

Salicylic acid

-
Glycolic Acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1427

Glycolic Acid

-
packaging

ampule of 3x1.5 mL

packaging

-

packaging

-

packaging

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

-

format

neat

format

neat

storage temp.

2-30°C

storage temp.

room temp

storage temp.

2-30°C

storage temp.

2-30°C

General description

Glacial Acetic Acid is a simple monocarboxylic acid, which is devoid of water. Pharmaceutically, it is commonly used as a topical antibiotic that treats infections caused by bacteria.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Glacial Acetic Acid may be used as a reference standard for the determination of the analyte in raw materials and pharmaceutical formulations by titrimetry and gas chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2954 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Pictograms

FlameCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

102.2 °F

Flash Point(C)

39 °C


Certificates of Analysis (COA)

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Glacial Acetic Acid
USP43/NF38: United States Pharmacopei and National Formulary
United States Pharmacopeia/National Formulary, 36(3), 77-77 (2018)
Part 5: Pharmaceutical Manufacturing
Remington: The Science and Practice of Pharmacy, 1083-1083 (2005)
Quantitative analysis of volatile fatty acids in aqueous solution by gas chromatography
Mahadevan V and Stenroos L
Analytical Chemistry, 39(13), 1652-1654 (1967)
B S Nagoba et al.
Journal of infection and public health, 6(6), 410-415 (2013-09-04)
Pseudomonas aeruginosa is a significant cause of burn wound infections and, skin and soft tissue infections. The antiseptic management is an integral part of the management of wound infections and is essential to control wound infection. Although commonly used, concerns

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