Skip to Content
MilliporeSigma
All Photos(1)

Documents

PHR1963

Supelco

(+)-Catechin

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

(+)-Catechin, (+)-Cyanidanol, D-Catechin

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C15H14O6
CAS Number:
Molecular Weight:
290.27
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1096790

API family

catechins

CofA

current certificate can be downloaded

packaging

pkg of 50 mg

application(s)

pharmaceutical

format

neat

storage temp.

2-8°C

SMILES string

O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m0/s1

InChI key

PFTAWBLQPZVEMU-DZGCQCFKSA-N

Looking for similar products? Visit Product Comparison Guide

General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

(+)-Catechin is a flavan-3-ol, that belongs to the family of polyphenolic flavonoids, called catechins. Found in green tea, it shows many health benefits, such as anti-oxidant, anti-inflammatory, anti-proliferative, and anti-platelet activity.

Application

This pharmaceutical secondary standard can also be used as follows:

  • Development of an ultra-high performance liquid chromatography-triple-quadrupole tandem mass spectrometry (UHPLC-MS-MS) method for the simultaneous determination of eight catechins and four theaflavins in three types of tea samples
  • Separation and estimation of six tea catechins and caffeine by an UHPLC method coupled to a UV detector from green tea samples
  • Simultaneous analysis of five naturally occurring catechins by an isocratic HPLC method
  • Infrared-assisted extraction (IRAE) followed by HPLC separation and quantification of catechin, epicatechin, and procyanidin B2 in grape seed samples
  • Analysis of caffeine and catechins from green tea leaves by pressurized liquid extraction (PLE) using ethyl lactate, water, and ethyl lactate + water mixtures

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2624 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 7

1 of 7

(−)-Epicatechin ≥98% (HPLC), from green tea

Sigma-Aldrich

E4018

(−)-Epicatechin

(−)-Epicatechin analytical standard

Supelco

68097

(−)-Epicatechin

Epicatechin primary reference standard

03940590

Epicatechin

(−)-Epicatechin ≥90% (HPLC)

Sigma-Aldrich

E1753

(−)-Epicatechin

(−)-Catechin gallate ≥98% (HPLC), from green tea

Sigma-Aldrich

C0692

(−)-Catechin gallate

Quercetin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1488

Quercetin

Epigallocatechin gallate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1333

Epigallocatechin gallate

Study on infrared-assisted extraction coupled with high performance liquid chromatography (HPLC) for determination of catechin, epicatechin, and procyanidin B2 in grape seeds
Cai Y, et al.
Food Chemistry, 127, 1872-1877 (2011)
Pressurized liquid extraction of caffeine and catechins from green tea leaves using ethyl lactate, water and ethyl lactate+ water mixtures
Bermejo DV, et al.
Food and Bioproducts Processing, 96, 106-112 (2015)
Giftson J Senapathy et al.
Molecules (Basel, Switzerland), 25(21) (2020-10-28)
Worldwide, lung cancer remains one of the leading cancers with increasing mortality rates. Though chemotherapy for lung cancer is effective, it is always accompanied by unavoidable and grave side effects. Photodynamic therapy (PDT), using novel photosensitizers, is an advanced treatment

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service