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S6297

Sigma-Aldrich

Sodium bicarbonate

BioXtra, 99.5-100.5%

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Synonym(s):
Sodium hydrogen carbonate
Linear Formula:
NaHCO3
CAS Number:
Molecular Weight:
84.01
Beilstein:
4153970
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

product line

BioXtra

Quality Level

Assay

99.5-100.5%

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.015% Insoluble matter

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

solubility

H2O: 1 M, clear, colorless

density

2.16 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.003%
sulfate (SO42-): ≤0.003%

cation traces

Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.005%
NH4+: ≤0.0005%
Pb: ≤0.0005%
Zn: ≤0.0005%

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

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This Item
71631SX032013433
Sodium bicarbonate BioXtra, 99.5-100.5%

Sigma-Aldrich

S6297

Sodium bicarbonate

Premium Grade
Sodium bicarbonate tested according to Ph. Eur.

Sigma-Aldrich

71631

Sodium bicarbonate

-
Sodium bicarbonate Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS

Supelco

SX0320

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Sodium bicarbonate puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E500, 99.0-100.5%, powder

Sigma-Aldrich

13433

Sodium bicarbonate

Essential Grade
assay

99.5-100.5%

assay

99.0-101.0%

assay

99.7-100.3% dry basis

assay

99.0-100.5%

form

powder

form

solid

form

powder

form

powder

impurities

≤0.0005% Phosphorus (P), ≤0.015% Insoluble matter

impurities

-

impurities

≤0.015% Insoluble matter

impurities

ammonia (NH3), in accordance, organic volatile impurities, complies, residual solvents, complies, water-insoluble matter, complies, ≤0.002% ammonium (NH4), complies

solubility

H2O: 1 M, clear, colorless

solubility

water: soluble 50 g/L

solubility

96 g/L

solubility

-

density

2.16 g/mL at 25 °C (lit.)

density

2.16 g/mL at 25 °C (lit.)

density

2.16 g/mL at 25 °C (lit.)

density

2.16 g/mL at 25 °C (lit.)

Application

Sodium bicarbonate has been used to supplement:
  • McCoy′s 5A medium to culture cell line BCRC 60187
  • minimum essential medium α (MEMα) to culture rat skeletal myoblasts
  • F-12K medium to culture bioartificial pancreas (BAP)

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This
Joshua C Tremblay et al.
The Journal of physiology, 593(3), 723-737 (2014-11-25)
Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown mechanisms. Oral administration of acetazolamide blunts the pulmonary vascular pressure response to acute hypoxia, thus permitting the observation of IPAVA blood flow with minimal
Roberto J Diaz et al.
American journal of physiology. Cell physiology, 306(12), C1191-C1199 (2014-04-25)
We have previously shown that ischemic preconditioning (IPC) protection against necrosis in whole hearts and in both fresh and cultured cardiomyocytes, as well as the improved regulatory volume decrease to hypoosmotic swelling in cardiomyocytes, is abrogated through Cl(-) channel blockade

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