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S6014

Sigma-Aldrich

Sodium bicarbonate

ACS reagent, ≥99.7%

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Synonym(s):
Sodium hydrogen carbonate
Linear Formula:
NaHCO3
CAS Number:
Molecular Weight:
84.01
Beilstein:
4153970
EC Number:
MDL number:
PubChem Substance ID:

grade

ACS reagent

Quality Level

Agency

suitable for EPA 1621
suitable for EPA 300

Assay

≥99.7%
99.7-100.3%

form

powder

impurities

≤0.015% Insoluble matter

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

density

2.16 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.003%
phosphate (PO43-): ≤0.001%
sulfur compounds (as SO42-): ≤0.003%

cation traces

Ca: ≤0.02%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.005%
NH4+: ≤5 ppm
heavy metals: ≤5 ppm (by ICP-OES)

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

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This Item
13433SX0320S8875
Sodium bicarbonate ACS reagent, ≥99.7%

Sigma-Aldrich

S6014

Sodium bicarbonate

-
Sodium bicarbonate puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E500, 99.0-100.5%, powder

Sigma-Aldrich

13433

Sodium bicarbonate

Essential Grade
Sodium bicarbonate Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS

Supelco

SX0320

Sodium bicarbonate

-
Sodium bicarbonate ReagentPlus®, ≥99.5%, powder

Sigma-Aldrich

S8875

Sodium bicarbonate

-
assay

≥99.7%, 99.7-100.3%

assay

99.0-100.5%

assay

99.7-100.3% dry basis

assay

≥99.5%

form

powder

form

powder

form

powder

form

powder

impurities

≤0.015% Insoluble matter

impurities

ammonia (NH3), in accordance, organic volatile impurities, complies, residual solvents, complies, water-insoluble matter, complies, ≤0.002% ammonium (NH4), complies

impurities

≤0.015% Insoluble matter

impurities

-

density

2.16 g/mL at 25 °C (lit.)

density

2.16 g/mL at 25 °C (lit.)

density

2.16 g/mL at 25 °C (lit.)

density

2.16 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.003%, phosphate (PO43-): ≤0.001%, sulfur compounds (as SO42-): ≤0.003%

anion traces

carbonate (CO32-): in accordance, chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤100 mg/kg

anion traces

chloride (Cl-): ≤0.003%, phosphate (PO43-): ≤0.001%, sulfur compounds (as SO42-): ≤0.003%

anion traces

-

General description

Sodium Bicarbonate, also known as baking soda, is commonly used as a mild base to neutralize acidic spills, regulate pH levels, and counteract the effects of certain acidic toxins in the body. It also acts as a leavening agent by generating CO when reacts with acidic ingredients like vinegar or lemon juice.

Application

Sodium bicarbonate is used as a:

  • mild base to neutralize the reaction mixture during the synthesis of 1,2:5,6-Di-O-cyclohexylidene-D-mannitol, and 2,3-Cyclohexylidene-D-glyceraldehyde.
  • precipitating agent in the co-precipitation method in the synthesis of gamma alumina (γ-Al2O3) catalyst during the methanol dehydration reaction to produce Dimethyl ether.
  • a pore-forming agent and CO2 source to enhance the substrate porosity during the formation of a porous poly(ethersulfone) support layer for designing high-performance thin-film composite forward osmosis (TFC-FO) membranes.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This
Joshua C Tremblay et al.
The Journal of physiology, 593(3), 723-737 (2014-11-25)
Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown mechanisms. Oral administration of acetazolamide blunts the pulmonary vascular pressure response to acute hypoxia, thus permitting the observation of IPAVA blood flow with minimal
Roberto J Diaz et al.
American journal of physiology. Cell physiology, 306(12), C1191-C1199 (2014-04-25)
We have previously shown that ischemic preconditioning (IPC) protection against necrosis in whole hearts and in both fresh and cultured cardiomyocytes, as well as the improved regulatory volume decrease to hypoosmotic swelling in cardiomyocytes, is abrogated through Cl(-) channel blockade

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