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159417

Sigma-Aldrich

Hydroxylamine hydrochloride

ReagentPlus®, 99%

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Synonym(s):
Hydroxylammonium chloride
Linear Formula:
NH2OH · HCl
CAS Number:
Molecular Weight:
69.49
Beilstein/REAXYS Number:
3539763
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor pressure

0.001 hPa ( 50 °C)

Quality Level

product line

ReagentPlus®

assay

99%

form

crystalline

technique(s)

inhibition assay: suitable

pH

2.5-3.5 (20 °C, 50 g/L)

mp

155-157 °C (dec.) (lit.)

density

1.67 g/mL at 25 °C (lit.)

SMILES string

Cl.NO

InChI

1S/ClH.H3NO/c;1-2/h1H;2H,1H2

InChI key

WTDHULULXKLSOZ-UHFFFAOYSA-N

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1 of 4

This Item
55460255580379921
Hydroxylamine hydrochloride ReagentPlus®, 99%

159417

Hydroxylamine hydrochloride

-
Hydroxylamine hydrochloride puriss. p.a., ACS reagent, ≥99.0% (RT)

55460

Hydroxylamine hydrochloride

Essential Grade
Hydroxylamine hydrochloride ACS reagent, 98.0%

255580

Hydroxylamine hydrochloride

-
Hydroxylamine hydrochloride 99.995% trace metals basis

379921

Hydroxylamine hydrochloride

-
assay

99%

assay

≥99.0% (RT)

assay

98.0%

assay

99.995% trace metals basis

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

density

1.67 g/mL at 25 °C (lit.)

density

1.67 g/mL at 25 °C (lit.)

density

1.67 g/mL at 25 °C (lit.)

density

1.67 g/mL at 25 °C (lit.)

pH

2.5-3.5 (20 °C, 50 g/L)

pH

2.5-3.5 (25 °C, 50 mg/mL in H2O)

pH

2.5-3.5 (20 °C, 50 g/L)

pH

2.5-3.5 (20 °C, 50 g/L)

mp

155-157 °C (dec.) (lit.)

mp

155-157 °C (dec.) (lit.)

mp

155-157 °C (dec.) (lit.)

mp

155-157 °C (dec.) (lit.)

General description

Hydroxylamine hydrochloride (Hydroxylammonium chloride) participates in the synthesis of 1,2,4-oxadiazoles, secondary amides and tertiary amides.
Hydroxylamine hydrochloride (NH2OH.HCl) is a hygroscopic salt widely used as a reactant in electrophilic substitution reactions, oxidation, and reduction reactions. It is also used in the synthesis of nitriles, pyrazoles, isoxazoles, nitrones, and pyridine.

Application

Hydroxylamine hydrochloride can be used as a reactant:
  • in the synthesis of primary amides from aldehydes in the presence of cesium carbonate (Cs2CO3) as a catalyst.
  • in the conversion of alicyclic /aliphatic carbonyl compounds and the aromatic aldehydes into corresponding oximes.
  • in the one-pot synthesis of nitriles from aldehydes in the presence of sodium sulfate (anhyd) and sodium bicarbonate catalysts.
  • It can also be used as a reducing agent in the preparation of single-layer reduced graphene oxide (RGO) sheets and films.

Biochem/physiol Actions

MAO inhibitor; inhibits platelet aggregation.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

target_organs

spleen

Storage Class

8B - Non-combustible, corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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