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Potassium chloride

ReagentPlus®, ≥99.0%

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Quality Level

product line





powder or crystals


5.5-8.5 (20 °C, 50 g/L)


770 °C (lit.)


1.98 g/mL at 25 °C (lit.)

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General description

Potassium chloride (KCl) is an inorganic salt commonly used in fertilizer industry. Its generation via chlorination of microcline has been reported. The intrinsic and extrinsic conductivity of KCl crystals have been measured. The impact of KCl on the activity of mitochondrial membrane, cristae and matrix proteins has been investigated. It facilitates the preparation of isoxazolines in aqueous medium.


Potassium chloride has been used in the preparation of perfusion buffer stock solution (1X).
It has been used in the preparation of the following buffers for small unilamellar vesicles (SUVs) preparation:
  • Escherichia coli supported lipid bilayer (SLB) buffer
  • extract buffer (XB)
  • high-salt extract buffer (HS-XB)
May be used for the preparation of phosphate buffered saline, and for the extraction and solubilization of proteins.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Storage Class

13 - Non Combustible Solids




Not applicable


Not applicable

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Coculture between hMADS and Mouse Adult CM.
Figeac F, et al.
Bio-protocol, 4(14) (2014)
Using supported bilayers to study the spatiotemporal organization of membrane-bound proteins.
Nguyen PA, et al.
Methods in Cell Biology, 128, 223-241 (2015)
Electrical Conductivity of Potassium Chloride.
Fuller RG, et al.
Physical Review Letters, 20(13), 662-662 (1968)
An environmentally benign synthesis of isoxazolines and isoxazoles mediated by potassium chloride in water.
Han L, et al.
Tetrahedron Letters, 55(14), 2308-2311 (2014)
Suman Mishra et al.
International journal of proteomics, 2015, 647408-647408 (2016-01-20)
Potassium chloride (KCl) has been commonly used in homogenization buffer and procedures of protein extraction. It is known to facilitate release of membrane-associated molecules but the higher concentration of KCl may affect the integrity of mitochondria by breaching the electrostatic

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