14470

1,4-Bis(acryloyl)piperazine

BioXtra, suitable for electrophoresis, ≥99.0% (TLC)

• Synonym(s): 1,4-Di(acryloyl)piperazine, N,N′-Bis(acryloyl)piperazine, BAP, PDA, Piperazine diacrylamide
• Empirical Formula (Hill Notation): C₁₀H₁₄N₂O₂
• CAS Number: 6342-17-2
• Molecular Weight: 194.23
• Beilstein/REAXYS Number: 745431
• MDL number: MFCD00077661
• UNSPSC Code: 41105319
• PubChem Substance ID: 329750497
• NACRES: NA.26

Properties

• product line: BioXtra
• Quality Level: 100
• assay: ≥99.0% (TLC)
• form: solid
• technique(s): electrophoresis: suitable
• impurities: ≤0.05% free acrylic acid
• mp: 91.5-93.5 °C (lit.)
• anion traces: chloride (Cl^-): ≤200 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• suitability: suitable for electrophoresis
• storage temp.: 2-8°C
• SMILES string: C=CC(=O)N1CCN(CC1)C(=O)C=C
• InChI: 1S/C10H14N2O2/c1-3-9(13)11-5-7-12(8-6-11)10(14)4-2/h3-4H,1-2,5-8H2
• InChI key: YERHJBPPDGHCRJ-UHFFFAOYSA-N

Description

Application

• Fabrication and application of zwitterionic phosphorylcholine functionalized monoliths with different hydrophilic crosslinkers in hydrophilic interaction chromatography: This study demonstrates the effective use of 1,4-Bis(acryloyl)piperazine as a crosslinker in creating zwitterionic monoliths for chromatographic applications, highlighting its utility in enhancing polymer interactions and selectivity in separation processes (Wang et al., 2020).


• Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles: This application uses a derivative concept where 1,4-Bis(acryloyl)piperazine could theoretically enhance the self-assembly and stability of redox-sensitive polymeric nanoparticles, offering insights into controlled release and targeted drug delivery systems (Ranucci et al., 2008).

Other Notes

Used as a vinylating agent for graft-copolymerization of different enzymes to cellulose, dextran, or starch; New crosslinking agent for polyacrylamide gels with improved protein separation and detection by silver staining; Increased resolution in 2D-protein electrophoresis.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves