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Sigma-Aldrich

MAPTRIX-M-VAEIDGIEL

Tenascin-C Mimetic, aqueous solution

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NACRES:
NA.75

sterility

Filtered sterilized solution

form

aqueous solution

mol wt

~23.5 kDa

packaging

pkg of 2.5 mg

concentration

0.5 mg/mL protein

technique(s)

cell culture | mammalian: suitable

binding specificity

Receptor: α9β1
Binding Motif: VAEIDGIEL

shipped in

ambient

storage temp.

2-8°C

Related Categories

Application

MAPTrix Technology provides a true extracellular microenvironment (ECM) by presenting combinatorial peptide motifs. The ECM, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions.Currently existing technology offers simple and merely adequate environments that facilitate simple cell processes such as cellular adhesion. The simple presentation of cell adhesion motifs is not optimal for controlling more integrated processes. Crosstalk among signaling pathways act synergistically to enhance cellular responses such as cell adhesion or proliferation. A study showed that a combination of extracellular matrix derived peptides presented on a surface may enhance cell adhesion strength and focal adhesion assembly. The combinatorial presentation of ECM peptides on cell growth surfaces may also promote elevated proliferation rates of primary or stem cells.

Features and Benefits

  • Biochemically-defined, animal-free cell culture surfaces designed to enhance cell performance
  • MAPTrix produces a uniform ECM surface that provides a highly controlled 2D extracellular microenvironment for cell cultures and related applications
  • Adhesion properties of the mussel adhesive protein makes the coating reproducible & reliable

Legal Information

MAPTrix is a trademark of Kollodis Biosciences

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


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