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51416C

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Minimum Essential Medium

with Earle′s Balanced Salts, with non-essential amino acids, without L-glutamine, liquid, sterile-filtered, suitable for cell culture

Pharma Manufacturing

Synonym(s):

Minimum Essential Medium Eagle, MEM

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.75

description

for research or for further manufacturing use

Quality Level

sterility

sterile-filtered

form

liquid

technique(s)

cell culture | mammalian: suitable

components

Earle’s salts (5% CO2): yes
L-glutamine: no

shipped in

ambient

storage temp.

2-8°C

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General description

Minimum Essential Medium (MEM), developed by Harry Eagle is one of the most widely used synthetic cell culture media.

Application

Minimum Essential Medium has been used to culture U87 cells (glioblastoma cell line), to study the antitumor action of decane-1,2-diol derivatives. It has also been used to culture SK-Mel-28 (melanoma cell line) cells.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib
Ladds MJGW, et al.
PLoS ONE, 13(4), e0195956-e0195956 (2018)
Aaminah Khan et al.
Oncogene, 39(17), 3555-3570 (2020-03-04)
Amplification of the MYCN oncogene occurs in ~25% of primary neuroblastomas and is the single most powerful biological marker of poor prognosis in this disease. MYCN transcriptionally regulates a range of biological processes important for cancer, including cell metabolism. The
Anisha Viswanathan et al.
Cells, 8(12) (2019-12-18)
Glioblastoma (GB), a grade IV glioma, with high heterogeneity and chemoresistance, obligates a multidimensional antagonist to debilitate its competence. Considering the previous reports on thioesters as antitumor compounds, this paper investigates on use of this densely functionalized sulphur rich molecule
Anisha Viswanathan et al.
European journal of pharmacology, 837, 105-116 (2018-09-05)
Glioblastoma remains the most common and aggressive type of malignant brain tumor among adults thus, considerable attention has been given to discovery of novel anti-tumor drugs for its treatment. This study reports the synthesis of a series of twelve novel
Marcus J G W Ladds et al.
PloS one, 13(4), e0195956-e0195956 (2018-04-24)
Tenovin-6 is the most studied member of a family of small molecules with antitumour activity in vivo. Previously, it has been determined that part of the effects of tenovin-6 associate with its ability to inhibit SirT1 and activate p53. However

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