71729

Sodium dodecyl sulfate

≥98.0% (GC)

• Synonym(s): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• Beilstein/REAXYS Number: 3599286
• EC Number: 205-788-1
• MDL number: MFCD00036175
• UNSPSC Code: 12161900
• eCl@ss: 39093306
• PubChem Substance ID: 57652354
• NACRES: NA.21

Properties

• description: anionic
• Quality Level: 200
• assay: ≥98.0% (GC)
• form: rod
• mol wt: micellar avg mol wt 18,000
• aggregation number: 62
• loss: ≤5% loss on drying
• CMC: 7-10 mM (20-25°C)
• mp: 204-207 °C (lit.)
• transition temp: cloud point >100 °C

Description

Application

Anionic detergent

Sodium dodecyl sulfate has been used in western blot lysis buffer[1] and also to prepare SDS-loading dye.[2]

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS)/lauryl sulfate, an ionic detergent has the ability to distract biological membranes. It can block RNase and deoxyribonuclease (DNase) activity. SDS is one of the main constituents of several reagents, that are used to purify nucleic acids.[3] It is also considered as a permeability enhancer in oral formulations.[4]

Safety Information

• Pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H315,H318,H412
• pcodes: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: 338.0 °F
• flash_point_c: 170 °C
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges