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Key Documents

905

Sigma-Aldrich

Naphthol AS-D Chloroacetate

Synonym(s):

Naphthol AS-D chloroacetate, 3-Hydroxy-2-naphthoic-o-toluidide chloroacetate

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About This Item

Empirical Formula (Hill Notation):
C20H16ClNO3
CAS Number:
Molecular Weight:
353.80
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.47

form

powder

Quality Level

IVD

for in vitro diagnostic use

application(s)

hematology
histology

shipped in

dry ice

storage temp.

−20°C

SMILES string

Cc1ccccc1NC(=O)c2cc3ccccc3cc2OC(=O)CCl

InChI

1S/C20H16ClNO3/c1-13-6-2-5-9-17(13)22-20(24)16-10-14-7-3-4-8-15(14)11-18(16)25-19(23)12-21/h2-11H,12H2,1H3,(H,22,24)

InChI key

FMVKYSCWHDVMGO-UHFFFAOYSA-N

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Components

Gelatin capsules contain 20 mg

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Ayako Fujimoto et al.
The Journal of veterinary medical science, 74(12), 1643-1646 (2012-07-21)
A case of mast cell sarcoma in a 5-month-old Holstein female calf is described. Macroscopically, enlargement of the spleen, lymph nodes, tonsils and kidneys was noted, and there were tumor masses in the neck region and on the pleura and
H Ruokonen
Acta dermato-venereologica, 72(2), 92-94 (1992-01-01)
We compared the number of mast cells in erythema multiforme lesions, in clinically healthy mucosa between the EM attacks and in healthy mucosa from healthy volunteers. The mast cell count in patients with erythema multiforme was numerically higher than in
U Schmidt et al.
British journal of haematology, 68(2), 175-180 (1988-02-01)
In chronic granulocytic leukaemia, hybridoid leucocytes can regularly be found. Light microscopically they contain a mixture of eosinophilic, basophilic and naphthol AS-D chloroacetate esterase-positive granules. The present study was done to clarify the ultrastructural composition of these cells. It could
Usefulness of naphthol-AS-D-chloroacetate esterase (NASDCAE) in the diagnosis of AML: report of a case.
D Mastrangelo et al.
Haematologica, 70(5), 428-430 (1985-09-01)
M R Baer et al.
Cancer, 63(11), 2192-2200 (1989-06-01)
Leukemia cutis was documented by biopsy in 18 of 877 patients (2%) with acute myelogenous leukemia (AML) seen at Roswell Park Memorial Institute (Buffalo, NY) between 1969 and 1986. French-American-British (FAB) types included four M2, one M3, ten M4, and

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