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A1910

Sigma-Aldrich

(±)-2-Amino-4-phosphonobutyric acid

solid

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Synonym(s):
(±)-AP-4
Empirical Formula (Hill Notation):
C4H10NO5P
CAS Number:
Molecular Weight:
183.10
MDL number:
PubChem Substance ID:
NACRES:
NA.32

form

solid

color

white

SMILES string

NC(CCP(O)(O)=O)C(O)=O

InChI

1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)

InChI key

DDOQBQRIEWHWBT-UHFFFAOYSA-N

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This Item
A7929165304AB15097
Anti-mGluR4 Antibody from rabbit

Sigma-Aldrich

AB15097

Anti-mGluR4 Antibody

color

white

color

-

color

white

color

-

Gene Information

human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)
rat ... Grin2b(24410)

Gene Information

human ... GRM1(2911), GRM2(2912), GRM3(2913), GRM4(2914), GRM6(2916), GRM7(2917), GRM8(2918)
rat ... Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418), Grm6(24419), Grm7(81672)

Gene Information

-

Gene Information

mouse ... Grm4(268934)

General description

(±)-2-Amino-4-phosphonobutyric acid or DL-AP4 is a group III nonselective metabotropic glutamate receptor (mGluR) agonist. L-2-amino-4-phosphonobutyric acid (L-Ap4) displays close to 500-fold selectivity for group III mGluRs.

Application

(±)-2-Amino-4-phosphonobutyric acid may be used as a glutamic acid receptor blocker in perfusion solution in the eye tissue electroretinography studies.

Biochem/physiol Actions

NMDA glutamate receptor antagonist.

Caution

Hygroscopic, store desiccated.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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