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A2786

Sigma-Aldrich

Adenine

BioReagent, suitable for cell culture

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Synonym(s):
6-Aminopurine, Vitamin B4
Empirical Formula (Hill Notation):
C5H5N5
CAS Number:
Molecular Weight:
135.13
Beilstein/REAXYS Number:
5777
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

biological source

synthetic

Quality Level

product line

BioReagent

assay

≥99%

form

powder

mol wt

Mw 135.13 g/mol

technique(s)

cell culture | mammalian: suitable

color

white to off-white

mp

>360 °C (lit.)

solubility

0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

room temp

SMILES string

Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

InChI key

GFFGJBXGBJISGV-UHFFFAOYSA-N

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1 of 4

This Item
A8626PHR1383A5665
vibrant-m

A2786

Adenine

vibrant-m

A8626

Adenine

vibrant-m

PHR1383

Adenine

vibrant-m

A5665

Adenine

technique(s)

cell culture | mammalian: suitable

technique(s)

UV/Vis spectroscopy: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | plant: suitable

form

powder

form

powder

form

-

form

powder

storage temp.

room temp

storage temp.

room temp

storage temp.

2-8°C

storage temp.

-

solubility

0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

0.5 M HCl: soluble 20 mg/mL, Grade III, colorless to faint yellow or tan

solubility

-

solubility

0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

General description

Adenine is a purine nucleobase, synthesized from inosine monophosphate(IMP). It is a nitrogenous heterocyclic aromatic compound.

Application

Adenine has been used:
  • a component of green medium used for the derivation of keratinocytes from plucked hair follicles
  • for the serial culture of adult murine keratinocytes
  • as a media component for SSEA4+ limbal stromal stem cell differentiation

Biochem/physiol Actions

Adenine is a component of important biomolecules such as adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). NAD and FAD forms the structure of DNA and RNA, and plays important role in protein synthesis. ATP is an energy source, that is essential for cellular respiration.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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