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C0780

Sigma-Aldrich

Creatine

anhydrous

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Synonym(s):
(α-Methylguanido)acetic acid, N-Amidinosarcosine
Linear Formula:
H2NC(=NH)N(CH3)CH2CO2H
CAS Number:
Molecular Weight:
131.13
Beilstein/REAXYS Number:
907175
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

grade

anhydrous

Quality Level

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

SMILES string

CN(CC(O)=O)C(N)=N

InChI

1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)

InChI key

CVSVTCORWBXHQV-UHFFFAOYSA-N

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1 of 4

This Item
C7477A3594A0876
Creatine anhydrous

C0780

Creatine

-
L-Cysteine hydrochloride anhydrous, from non-animal source, BioReagent, suitable for cell culture, ≥98.0%

C7477

L-Cysteine hydrochloride

Essential+ Grade
ACES BioPerformance Certified, ≥99.0%, suitable for cell culture

A3594

ACES

Premium Grade
N-Acetyl-D-leucine

A0876

N-Acetyl-D-leucine

-
grade

anhydrous

grade

anhydrous

grade

BioPerformance Certified

grade

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable, ligand binding assay: suitable

color

white

color

white to off-white

color

-

color

white

Application

Creatine (Cr) and phosphocreatine (PCr) are involved with rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s). Creatine may be used as a supplement to study its uptake mechanism and metabolism of action.

Biochem/physiol Actions

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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The pleiotropic effects of creatine (Cr) are based mostly on the functions of the enzyme creatine kinase (CK) and its high-energy product phosphocreatine (PCr). Multidisciplinary studies have established molecular, cellular, organ and somatic functions of the CK/PCr system, in particular
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