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C7786

Sigma-Aldrich

Conalbumin from chicken egg white

BioReagent, suitable for cell culture

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Synonym(s):
Ovotransferrin
CAS Number:
EC Number:
MDL number:
NACRES:
NA.75

biological source

chicken egg white

product line

BioReagent

form

powder

concentration

80-100 % protein Biuret

technique(s)

cell culture | mammalian: suitable

solubility

water: 25 mg/mL, clear to slightly hazy, pink

cation traces

Fe: ≤0.02%

UniProt accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

chicken ... TF(396241)

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This Item
C0880A5253A2512
vibrant-m

C7786

Conalbumin from chicken egg white

vibrant-m

C0880

Conalbumin from chicken egg white

vibrant-m

A5253

Albumin from chicken egg white

vibrant-m

A2512

Albumin from chicken egg white

technique(s)

cell culture | mammalian: suitable

technique(s)

gel permeation chromatography (GPC): suitable

technique(s)

bioconjugation: suitable

technique(s)

bioconjugation: suitable

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

300

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

form

powder

form

powder

form

powder

form

lyophilized powder

Gene Information

chicken ... TF(396241)

Gene Information

chicken ... TF(396241)

Gene Information

chicken ... OVAL(396058)

Gene Information

chicken ... OVAL(396058)

General description

Conalbumin, also referred to as ovotransferrin, is encoded by the avian transferrin gene in the oviduct. It is a monomeric glycoprotein consisting of 686 amino acids and is a member of transferrin family. Conalbumin is one among the abundant proteins present in the chicken egg white.

Application

Conalbumin has been used:
  • as a constituent of Leibovitz 15 (L15) medium involved in preparation of primary neuronal cultures
  • to study its adsorption property on a metal surface in the presence of an external electric potential
  • to determine its adsorption isotherms in anion exchange chromatography by multivariate analysis

Biochem/physiol Actions

Conablumin (aka ovotransferrin) is a glycoprotein derived from egg white with a sequence similar to serum transferrin, but with a different glycosylation pattern. It is a strong iron binder with antiviral and antibacterial activities.
Conalbumin facilitates the transport of iron to the developing embryo. It exhibits anti-microbial activity thus, conalbumin is used in various applications such as infant formula ingredient, a food additive, and an antimicrobial agent for enhancing animal health. In addition, it also acts as an antifungal, antiviral, anticancer, antioxidative, antihypertensive and immunoregulatory agent.

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Customers Also Viewed

Ovotransferrin: Structure, bioactivities, and preparation
Wu J and Acero-Lopez A
Food Research International, 46(2), 480-487 (2012)
Preparation of anionic polyelectrolyte modified magnetic nanoparticles for rapid and efficient separation of lysozyme from egg white
Chen J, et al.
Journal of Chromatography A, 1388, 43-51 (2015)
Adsorption characteristics of various proteins on a metal surface in the presence of an external electric potential
Htwe Ei, et al.
Colloids and Surfaces. B, Biointerfaces, 166, 262-268 (2018)
İrem Lütfiye Atasoy et al.
Journal of chemical neuroanatomy, 80, 19-26 (2016-12-05)
Intracellular aggregation of hyperphosphorylated tau in neurofibrillary tangles (NFTs) is a major neuropathological hallmark of taupathies such as Alzheimer's disease. Okadaic acid (OKA) is a potent inhibitor of PP2A, leading to abnormal tau phosphorylation. Brain-derived neurotrophic factor (BDNF) is a
Nicholas Field et al.
Journal of chromatography. A, 1510, 13-24 (2017-07-03)
The combination of multi-well plates and automated liquid handling is well suited to the rapid measurement of the adsorption isotherms of proteins. Here, single and binary adsorption isotherms are reported for BSA, ovalbumin and conalbumin on a strong anion exchanger

Articles

This page segues to comprehensive insights on how serum albumin and other important cell culture components affect the performance of serum-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of albumin. These insights may also be applied to ex vivo and tissue engineering applications.

For use as a marker in SDS-PAGE; Albumin from chicken egg white, For use as a marker in SDS-PAGE; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein

Chromatograms

application for HPLC

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